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New England Journal of Medicine, 2001 The term restless legs syndrome (RLS) was first introduced by Karl A Ekbom, a Swedish neurologist and surgeon, in 1945, although the earliest description of restless legs associated with sleep disabilities possibly came from Sir Thomas Willis, an English physician, in 1672.1 2 More recently, abnormal involuntary movements during sleep such as nocturnal
Chaudhuri, K Ray +2 more
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Is restless legs syndrome in Parkinson disease patients associated with any specific factor? [PDF]
Arquivos de Neuro-Psiquiatria, 2021 Background: Restless legs syndrome or Willis-Ekbom disease is a disorder characterized by unpleasant sensations associated with the need to mobilize the lower limbs.
Manoel Alves SOBREIRA-NETO +7 more
doaj +1 more source
The relationship between chronic kidney disease and restless legs syndrome and its effective factors. A case-control study. [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2021 I Restless legs syndrome (RLS), is a neurological disorder in which persons feel uncomfortable, especially at night, in the limbs and needs to move their legs. This condition worsens with rest.
Zahra Mousavi +3 more
doaj +1 more source
BMJ, 2012 This patient, who has had RLS for 12 years, describes how doctors’ lack of knowledge about the condition delayed effective treatment; she urges patients and doctors alike to become better ...
Algera, C., Lammers, G.J.
+13 more sources
Restless Legs Syndrome: The under-recognised condition [PDF]
Libyan Journal of Medicine, 2006 Up to 15% of the adult population experiences restless legs or Ekbom syndrome during their life [1]. The patients may present to a wide range of medical specialities such as general practitioners, general physicians, nephrologists, haematologists ...
Hani Benamer
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Women's Health, 2022 Objectives: The aim of this cross-sectional study was to examine the correlation between gestational age and number of previous pregnancies in group of pregnant women with restless legs syndrome and the connection of restless legs syndrome with family ...
Lucija Čondić Jurjević +1 more
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Experimental and Therapeutic Medicine, 2021 The aim of this overview was to outline the pathophysiology, common comorbidities and current therapeutic modalities in the treatment/management of restless legs syndrome (RLS) a sensorimotor neurological disorder. The main symptom in RLS is a compelling
Andrei Vlasie +4 more
semanticscholar +1 more source
A Randomized, Placebo‐Controlled Crossover Study with Dipyridamole for Restless Legs Syndrome
Movement Disorders, 2021 New pharmacological targets are needed for restless legs syndrome. Preclinical data suggest that a hypoadenosinergic state plays an important pathogenetic role.
D. Garcia-Borreguero +3 more
semanticscholar +1 more source
Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs
The Journal of Headache and Pain, 2022 Background Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contributions remain unclear. Objectives To identify the genetic variants of restless legs syndrome in migraineurs and to investigate their potential ...
Yun-Jin Jiang +10 more
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JAMA, 2017 Restless legs syndrome affects 5%–10% of the population, most commonly in women older than 35 years of age. Of all people seeking medical care, 2%–3% will have restless legs syndrome that affects their sleep, daytime productivity, cognition or mood, and will require treatment.[1][1 ...
Philippe Rizek, Niraj Kumar
openaire +6 more sources