Results 21 to 30 of about 74,790 (316)

A Randomized, Placebo‐Controlled Crossover Study with Dipyridamole for Restless Legs Syndrome

Movement Disorders, 2021
New pharmacological targets are needed for restless legs syndrome. Preclinical data suggest that a hypoadenosinergic state plays an important pathogenetic role.
D. Garcia-Borreguero, Celia Garcia-Malo, J. Granizo, S. Ferré   +3 more
semanticscholar   +1 more source

Restless legs syndrome [PDF]

Clinical Medicine, 2016
Restless legs syndrome (RLS), also known as Willis-Ekbom disease (WED), is a common movement disorder characterised by an uncontrollable urge to move because of uncomfortable, sometimes painful sensations in the legs with a diurnal variation and a release with movement.
Lisa, Klingelhoefer, Kalyan, Bhattacharya, Heinz, Reichmann   +2 more
openaire   +2 more sources

Genome-wide analysis identified novel susceptible genes of restless legs syndrome in migraineurs

The Journal of Headache and Pain, 2022
Background Restless legs syndrome is a highly prevalent comorbidity of migraine; however, its genetic contributions remain unclear. Objectives To identify the genetic variants of restless legs syndrome in migraineurs and to investigate their potential ...
Yun-Jin Jiang, Cathy Shen-Jang Fann, Jong-Ling Fuh, Ming-Yi Chung, Hui-Ying Huang, Kuo-Chang Chu, Yen-Feng Wang, Chia-Lin Hsu, Lung-Sen Kao, Shih-Pin Chen, Shuu-Jiun Wang   +10 more
doaj   +1 more source

The prevalence of Restless Legs Syndrome/Willis-ekbom disease (RLS/WED) in the third trimester of pregnancy:a systematic review [PDF]

, 2020
BACKGROUND: RLS is known as one of the most common movement disorders during pregnancy, which is most aggravated in the third trimester of pregnancy and can affect up to one-third of pregnant women. This study intends to determine the total prevalence of
Abdi, Alireza, Daneshkhah, Alireza, Darvishi, Fateme, Darvishi, Niloofar, Jalali, Rostam, Khaledi-Paveh, Behnam, Mohammadi, Masoud, Salari, Nader, Vaisi-Raygani, Aliakbar   +8 more
core   +1 more source

The effect of black seed oil massage on the severity of restless legs syndrome in patients with type 2 diabetes [PDF]

مجله علوم پزشکی فیض (پیوسته), 2023
Background: Considering that traditional medicine has been used to treat sleep disorders due to restless leg syndrome, the aim of the present study was to determine the effect of black seed oil massage on the severity of restless legs syndrome in ...
Zohre Khalaj, Mansour Dianati, Zahra Sooki   +2 more
doaj   +2 more sources

Migraine and restless legs syndrome – is there an association?

Neurologijos seminarai, 2023
Migraine and restless legs syndrome are diseases that disturb the normal quality of human life. Moreover, comorbidity of these disorders determines even more difficult condition of the patients.
D. Bučaitė, J. Normantas, G. Žemgulytė   +2 more
doaj   +3 more sources

Genome-wide association analysis of insomnia complaints identifies risk genes and genetic overlap with psychiatric and metabolic traits. [PDF]

, 2017
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesPersistent insomnia is among the most frequent complaints in general practice ...
A Bettolo, A Clark, A Kong, A Subramanian, AD Skol, AG Harvey, AN Vgontzas, Anke R Hammerschlag, B Feige, B Han, B Zhang, Barbara Schormair, Bart H W te Lindert, BK Bulik-Sullivan, C Baglioni, C Sudlow, CA de Leeuw, CH Bastien, Christiaan A de Leeuw, CJ Willer, CM Morin, CM Morin, CM Morin, D-J Dijk, Danielle Posthuma, DF Gudbjartsson, DJ Buysse, EC Schulte, EM Byrne, Erdogan Taskesen, Eus J W Van Someren, FP Cappuccio, G Kichaev, G Lassi, Gudmar Thorleifsson, H Morphy, Hreinn Stefansson, HU Wittchen, Ingileif Jonsdottir, J Marchini, J Winkelmann, J Winkelmann, J Yang, JM Lane, JM Lane, Juergen Wellmann, Juliane Winkelmann, K Spiegelhalder, Kari Stefansson, Kim Dekker, Klaus Berger, Konrad Oexle, Kyoko Watanabe, L Mallon, L Palagini, L Xiong, M Cai, MDM Leiserson, MH Bonnet, MJ Lind, MM Ohayon, N Amin, NE Allen, P-R Loh, PM Nilsson, PM Visscher, R Ursin, Rick Wassing, RP Allen, RR Bootzin, S Beaulieu-Bonneau, S Purcell, S Razick, S Redline, SE Jones, Suzanne Sniekers, Sven Stringer, SW Schwartz, T Paparrigopoulos, TA Hargens, Tessa F Blanken, Thorarinn Gislason, V Tucci, Y Dauvilliers, YK Wing, YW Cho   +85 more
core   +9 more sources

Restless legs syndrome [PDF]

BMJ, 2012
This patient, who has had RLS for 12 years, describes how doctors’ lack of knowledge about the condition delayed effective treatment; she urges patients and doctors alike to become better ...
Algera, C., Lammers, G.J.
openaire   +6 more sources

Restless Legs Syndrome across the Lifespan: Symptoms, Pathophysiology, Management and Daily Life Impact of the Different Patterns of Disease Presentation

International Journal of Environmental Research and Public Health, 2020
Restless legs syndrome is a common but still underdiagnosed neurologic disorder, characterized by peculiar symptoms typically occurring in the evening and at night, and resulting in sleep disruption and daily functioning impairment.
G. Didato, R. di Giacomo, Giuseppa Jolanda Rosa, A. Dominese, M. de Curtis, P. Lanteri   +5 more
semanticscholar   +1 more source

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis

Lancet Neurology, The, 2017
Barbara Schormair, Steven Bell, Aaro V Salminen   +2 more
exaly   +2 more sources