Results 151 to 160 of about 1,147,765 (344)
Snhg18 regulates Yap subcellular localization to maintain bone homeostasis
Nature CommunicationsOsteoporosis treatments commonly mitigate bone loss but rarely restore lost bone mass. Yes-associated protein (Yap) nuclear translocation is crucial for the osteogenic differentiation of bone marrow stromal cells (BMSCs), but is disrupted by many factors
Jie Huang +8 more
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FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Land use and cover change accelerated China’s land carbon sinks limits soil carbon
npj Climate and Atmospheric ScienceLand use and cover change (LUCC) significantly impacts global carbon cycles and land surface properties, accounting for 25% of the historical atmospheric CO2 increase.
Yue Cheng +8 more
doaj +1 more source
Restoration of Occlusal Vertical Dimension in Dental Erosion Caused by Gastroesophageal Reflux: Case Report [PDF]
, 2010 Eduardo Galia Reston +4 more
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Annual Variation of Secondary Productivity of Macroben-Thos Based on Brey Estimation Model
Haiyang Kaifa yu guanliIn this study, we took the East Fujian ecological monitoring area as an example, using Brey's empirical formula to analyzed the characteristics of Macrobenthos Community Structure and the interannual variation of secondary productivity based on the ...
CHENG Hong +7 more
doaj
Restoration of above canopy reference hemispherical image from below canopy measurements for plant area index estimation in forests/ Metsa võrastiku läbipaistvuse mõõtmine digitaalsete poolsfäärikaamerate abil [PDF]
, 2013 Mait Lang, Ave Kodar, Tauri Arumäe
openalex +1 more source