Results 101 to 110 of about 14,052 (291)
Restorative practices: Fostering healthy relationships and promoting positive discipline in schools
, 2014 Humans are born to learn, but we don’t learn in isolation. We learn based on positive relationships and interactions with peers and in environments like schools that foster opportunities for students and staff to learn and grow together.
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Assessing the restorative effects of observing a video of dog play in urban dog parks using EEG
Human-Animal InteractionsContact with nature is restorative and leads to health benefits via nearby nature such as gardens, natural scenes, and interactions with companion animals.
Hyung-Sook Lee, Jeong-Yeon Lee
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Therapeutic landscapes, restorative environments, place attachment, and wellbeing
, 2018 Evidence of declining well-being and increasing rates of depression and other mental illnesses has been linked with modern humans’ separation from nature.
Weerasuriya, R. +7 more
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Industrial Brownfields as Restorative Environments: the Possibility of Transformation and Reactivation of the Abandoned Industrial Heritage [PDF]
, 2020 Changes in the needs of modern society, as well as technical and technological developments, have led to an increase in the number of abandoned industrial buildings in cities, thereby disrupting existing urban areas.
Barać, Mirjana +3 more
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Frontiers in PsychologyIntroductionChronic stress and the lack of restorative environments negatively impact behavioral health, especially in isolated, confined, or operational settings.
Renee Abbott +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source