Results 91 to 100 of about 14,052 (291)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Soundscape Restorativeness and Its Influencing Factors in University Teaching Zones
BuildingsUniversity campus teaching areas are essential spaces for students’ daily learning and recovery, in which soundscapes play a crucial role in shaping restorative experiences.
Yaping Wang, Xiaolin Zhang, Qiyu Duan
doaj +1 more source
Using Virtual Reality to Bring Restorative Environments to Employees: An Online Pilot Study. [PDF]
Int J Environ Res Public Health, 2023 Horan KA +4 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Behavioral Sciences, 2014 Physical settings can play a role in coping with stress; in particular experimental research has found strong evidence between exposure to natural environments and recovery from physiological stress and mental fatigue, giving support to both Stress ...
Rita Berto
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Frontiers in Environmental ScienceIn the face of mounting pressures in modern society, research into restorative environments has emerged as a crucial field addressing issues related to mental health and environmental wellbeing.
Zihan Yang, Zhigang Tu, Zhongshan Huang
doaj +1 more source
Designed natural spaces: Informal gardens are perceived to be more restorative than formal gardens
Frontiers in Psychology, 2016 Experimental research shows that there are perceived and actual benefits to spending time in natural spaces compared to urban spaces such as reduced cognitive fatigue, improved mood, and reduced stress.
Elyssa eTwedt +2 more
doaj +1 more source
Beyond Blue and Green Spaces: Identifying and Characterizing Restorative Environments on Sichuan Technology and Business University Campus. [PDF]
Int J Environ Res Public Health, 2022 Du Y, Zou Z, He Y, Zhou Y, Luo S.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source