Results 71 to 80 of about 12,055 (255)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Folk Festivals as Restorative Environments Based on Attention Restoration Theory-The Roles of Liminal Experience and Timing. [PDF]

Psychol Res Behav Manag, 2023
Dai X, Tang S.
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Measuring restoration quality in urban forest greenways: insights for planning and management

Frontiers in Psychology
IntroductionGreenways play a crucial role in enhancing citizens’ quality of life by providing restorative environments, particularly in settings such urban forests.
Hong Wang, Yuxiang Liu, Ming-Juan Zhang, Xinxin Wang   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Soundscape Restorativeness and Its Influencing Factors in University Teaching Zones

Buildings
University campus teaching areas are essential spaces for students’ daily learning and recovery, in which soundscapes play a crucial role in shaping restorative experiences.
Yaping Wang, Xiaolin Zhang, Qiyu Duan
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Advances, hotspots, and trends in restorative environment research over the past 30 years: a bibliometric analysis based on the WoS database

Frontiers in Environmental Science
In the face of mounting pressures in modern society, research into restorative environments has emerged as a crucial field addressing issues related to mental health and environmental wellbeing.
Zihan Yang, Zhigang Tu, Zhongshan Huang
doaj   +1 more source

The Role of Nature in Coping with Psycho-Physiological Stress: A Literature Review on Restorativeness

Behavioral Sciences, 2014
Physical settings can play a role in coping with stress; in particular experimental research has found strong evidence between exposure to natural environments and recovery from physiological stress and mental fatigue, giving support to both Stress ...
Rita Berto
doaj   +1 more source