Results 51 to 60 of about 14,052 (291)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Restorative effects and perception of nature-themed artworks in indoor environments: an empirical study based on VR+EEG

Frontiers in Psychology
BackgroundWhile numerous studies have examined the restorative effects of natural elements in indoor environments, limited attention has been given to the role of natural analogues. This study investigates the restorative effects of nature-themed artwork,
Jiayin Chen, Huiqiu Zhu, Yue Cheng, Henan Yin, Minzhe Yi, Danni Shen, Zuyao Zhang, Jue Wu   +7 more
doaj   +1 more source

The Restorative Quality of the Work Environments: The Moderation Effect of Environmental Resources between Job Demands and Mindfulness

Social Sciences, 2023
In the work context, employees must cope with everyday demands, which deplete psychological resources (e.g., direct attention and concentration). The environment’s perceived quality (i.e., perceived restorativeness) helps people recover from job demands ...
Diego Bellini, Barbara Barbieri, Michela Loi, Marina Mondo, Silvia De Simone   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Enhancing Restoration in Urban Waterfront Spaces: Environmental Features, Visual Behavior, and Design Implications

Buildings
Urbanization poses mental health risks for urban dwellers, whereas natural environments offer mental health benefits by providing restorative experiences through visual stimuli.
Shiqin Zhou, Chang Lin, Quanle Huang
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

On the use and experience of a health garden [PDF]

, 2011
During the last decades an increasing amount of research suggests that a stay in a natural environment could reduce stress and help people restore. Furthermore, several decades of horticultural therapy have shown good outcomes in treating for example ...
Tenngart Ivarsson, Carina
core  

Measuring the perceived restorativeness of soundscapes : is it about the sounds, the person, or the environment? [PDF]

, 2013
To determine the ‘restorative aspects of sound exposure’ a reliable and valid measure is needed. A Perceived Restorativeness Soundscape Scale (PRSS), which measures the level of Fascination, Being-Away, Compatibility, and Extent (FACE), has been ...
Guastavino, Catherine, Payne, Sarah R., Payne, Sarah R   +2 more
core   +1 more source

A Study of Soundscape Restoration in Office-Type Pocket Parks

Buildings
High-density building environments and fast-paced working conditions in cities pose health challenges for office workers. Office-type pocket parks assume the social responsibility of providing restorative environments for office workers, and the ...
Yaping Wang, Xin Deng, Yanqiu Cui, Xin Zhao   +3 more
doaj   +1 more source