Results 41 to 50 of about 14,052 (291)

Reconsidering restorative environments for older adults:How the social context shapes restorative experiences [PDF]

In this rapidly ageing world, restorative experiences of older adults appear to be a relatively understudied yet critical area of research. Earlier studies showed that age-related changes in physical abilities, sensitivity to environmental stressors, and
Neven, Louis, Grave, Anne J.J.; id_orcid, Mohammadi, Masi   +2 more
core   +1 more source

THE CASCADE MODEL IN SYSTEMIC RESTORATIVE JUSTICE SOLUTIONS FOR JUVENILE REHABILITATION [PDF]

Probacja
The article highlights the rationale and need for implementing systemic restorative justice solutions within current juvenile rehabilitation practices.
Grzegorz Głupczyk
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

How Restorative Design in Aquatic Center Enhances User Learning Engagement: The Critical Role of Attention Restoration: An Environmental Psychology Approach with Implications for Sports Buildings

Buildings
With the increasing depth of research on built environments, theories of restorative environments and concepts of biophilic design have garnered widespread attention in the field of architecture.
Wenyue Liu, Xiaolong Chen, Hongfeng Zhang, Cora Un In Wong, Jianguo Qiu   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Visual properties and perceived restorativeness in green offices: a photographic evaluation of office environments with various degrees of greening

Frontiers in Psychology
Office environments play a critical role in employee wellbeing and productivity. While the benefits of incorporating nature into workspaces have been recognized, the specific visual characteristics that contribute to restorativeness remain unclear.
Seiji Shibata, Kenro Tokuhiro, Akinori Ikeuchi, Masakazu Ito, Hirotaka Kaji, Masayoshi Muramatsu   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Research on the restorative effects and perception of privacy driven activities in Chinese classical gardens—Case studies of three Suzhou gardens

Frontiers in Public Health
The need for privacy, recognized as a fundamental psychological requirement, has garnered increasing attention as researchers explore the restorative effects of privacy driven activities (PDA).
Hanxin Liu, Hanxin Liu, Guoshu Bin, Guoshu Bin, Xiao Wang, Xiao Wang, Jia Luo, Minyi Liu   +7 more
doaj   +1 more source

Human Preferences for the Visual Appearance of Desks: Examining the Role of Wooden Materials and Desk Designs

Buildings, 2023
Visually pleasing materials and furnishings may be an important component of pleasant, restorative indoor spaces, where people can rest, relax, and recover from stress.
Dean Lipovac, Michael D. Burnard
doaj   +1 more source