Results 111 to 120 of about 14,052 (291)

Designing Smart Urban Parks with Sensor-Integrated Landscapes to Enhance Mental Health in City Environments

Buildings
As mental health issues such as stress, anxiety, and depression become increasingly prevalent in urban populations, there is a critical need to embed restorative functions into the built environment.
Yuyang Cai, Yiwei Yan, Guohang Tian, Yiwen Cui, Chenfang Feng, Haoran Tian, Xiaxi Liuyang, Ling Zhang, Yang Cao   +8 more
doaj   +1 more source

Restorative Experiences of Regenerative Environments

Environment and Society
Abstract Environmental health influences personal wellbeing through direct experience. Despite this, the focus of the literature on the regeneration and reuse of post- industrial sites considers them as biophysical spaces studied conceptually rather than as places of physical engagement.
Robert France, Heather Braiden
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Restorative built indoor environments : Cafés as informal learning spaces in Malmö, Sweden

, 2023
Cities worldwide need to become healthier, both physically and mentally. While Sweden ranks highly on a global scale of sustainable urban development, the country is facing issues with the declining mental health of its citizens, notably affecting the ...
Grahn, Beatrice
core   +1 more source

Perception de l’effet restaurateur des environnements naturels et urbains en France

VertigO
In France, urbanisation continues to grow, leading its residents to have less and less contact with nature and its benefits. It is therefore imperative to undertake research into the beneficial effects of the restoration offered by natural spaces within ...
Florent Béclin, Thierry Kosinski, Stéphane Rusinek   +2 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

The restorative power of natural and built environments [PDF]

, 2008
This thesis explores the relationship between environmental affect and mental health using restorative theory as an organising framework. Environmental affect can be described as how the physical environment (home, park etc) and social context (being ...
Thompson, Catharine Ward, Roe, Jenny, Aspinall, Peter   +2 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Effect of Intentionally Engaging Attention when Viewing Restorative Environments: Exploring Attention Restoration Theory

, 2014
Although research exploring Attention Restoration Theory has been extensive, certain procedures for its study seem to be taken as implicit, but require investigation for a deeper understanding and application of both the theory and its underlying ...
Jaggard, Charles E.
core  

Restorative potential of greenspaces in noise-polluted environments (RESTORE)

Urban densification often entails an increase in noise burden and a reduction of green spaces. This exposes residents to more stress and impedes outdoor recreation. The RESTORE project investigated if and how far green spaces facilitate, and road traffic noise impedes restoration from stress. It followed a comprehensive research approach: i) laboratory
Tobias, Silvia, Schäffer, Beat, Kawai, Claudia, Dopico Magadan, Javier, Garcia Martin, Maria, Kolecka, Natalia, Schaupp, Julia, Bauer, Nicole, Georgiou, Fotis, Pieren, Reto, Wunderli, Jean Marc   +10 more
openaire   +2 more sources