Results 181 to 190 of about 5,596,824 (289)

Radiation‐Triggered Chemokine‐Secreting Probiotics for Boron Neutron Capture Therapy Based Radioimmunotherapy

Advanced Science, EarlyView.
Engineered Escherichia coli Nissle 1917 with a tannic acid‐mediated BPA coating enables tumor‐targeted boron delivery for BNCT. The low‐level incidental radiation generated during BNCT activate a RecA‐driven circuit to induce CXCL10, while radiation‐enhanced bacterial colonization triggers in situ vaccination and systemic antitumor immunity.
Yang Liu, Yuzhong Qian, Shaobo Huang, Bingbing Li, Yue Yu, Xiang Cheng, Chang Chen, Jiheng Wang, Maosong Yang, Lizheng Liang, Xiancai Meng, Zhigang Liu   +11 more
wiley   +1 more source

On the Relative Intrusiveness of Physical and Chemical Restraints

AJOB Neuroscience
De Marco, Gabriel, Douglas, Thomas, Forsberg, Lisa, Savulescu, Julian   +3 more
openaire   +2 more sources

The Ethical Problems of Prolonged Physical Restraint

, 1991
Strumpf, Neville E. and Evans, Lois K.
core   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

A service evaluation of restraint, seclusion and escalation in inpatient mental health care: a retrospective observational study in England

Ugwuocha NW, Bifarin O, Shoko C, Nielson S, Challinor A, Morgan D, Jones A, Hallett N, Joyce D.   +8 more
europepmc   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

Reply to Wang: Policy failure can be assessed from observed outcomes. [PDF]

Proc Natl Acad Sci U S A
He Y, Bu Y.
europepmc   +1 more source

Wetting‐Driven Transfer of Flexible Ultra‐Thin Temperature Sensors

Advanced Electronic Materials, EarlyView.
A wetting‐driven transfer approach enables ultra‐thin temperature sensors to be transferred from a super‐hydrophilic donor substrate onto rigid, curved, and biological receiver substrates. By combining controlled wetting with a conformal Parylene carrier layer, the method preserves stable thermal sensing performance while expanding the integration of ...
Hafiza Faiqa Maqsood, Annelot Nijkoops, Fahimeh Masoumi, Giuseppe Cantarella, Niko Münzenrieder, Riccardo Zamboni   +5 more
wiley   +1 more source

Incidence of Using Physical, Mechanical Restraints and Seclusion in Saudi Mental Health Settings: A Prospective Cohort Study. [PDF]

Healthcare (Basel)
Almutairi AS, Marsden A, Price O, Alqahtani AH, Almulhim AW, Alsaidan S, Alanazi M, Lovell K.   +7 more
europepmc   +1 more source

Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries

Advanced Energy Materials, EarlyView.
This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang, Luca Weckelmann, Baolin Wu, Chih‐Long Tsai, Luc Raijmakers, Rüdiger‐A. Eichel, Anna Windmüller   +6 more
wiley   +1 more source