Results 31 to 40 of about 65,038 (219)

Trust Region Plug-and-Play With Provable Convergence for Image Restoration

open access: yesIEEE Access
The Plug-and-Play (PnP) method is an optimization-based splitting algorithm that solves image inversion problems by combining data fidelity with a deep learning-based denoiser as an implicit regularization term.
Christian Budhi Sabdana   +4 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Dietary convergence induces individual responses in faecal microbiome composition

open access: yeseGastroenterology
Background Dietary variation has been identified as a key contributor to microbiome diversification. However, assessing its true impact in a cross-sectional setting is complicated by biological confounders and methodological hurdles. We aimed to estimate
Gwen Falony   +11 more
doaj   +1 more source

Sea surface currents and geographic isolation shape the genetic population structure of a coral reef fish in the Indian Ocean.

open access: yesPLoS ONE, 2018
In this contribution, we determine the genetic population structure in the Skunk Clownfish (Amphiprion akallopsisos) across the Indian Ocean, and on a smaller geographic scale in the Western Indian Ocean (WIO).
Filip Huyghe, Marc Kochzius
doaj   +1 more source

Precision photon spectra for wino annihilation

open access: yesJournal of High Energy Physics, 2019
We provide precise predictions for the hard photon spectrum resulting from neutral SU(2) W triplet (wino) dark matter annihilation. Our calculation is performed utilizing an effective field theory expansion around the endpoint region where the photon ...
Matthew Baumgart   +8 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Quad Rapidly-Exploring Random Tree Star Algorithm With Improved Potential Force for Unmanned Aerial Vehicle Path Planning

open access: yesIEEE Access
Rapidly-exploring random tree star (RRT*) has attracted intensive attention in track planning due to its asymptotic optimal properties. However, the RRT* algorithm plans costly trajectory paths.
Peng Bian   +4 more
doaj   +1 more source

Aerosol-induced changes of convective cloud anvils produce strong climate warming [PDF]

open access: yesAtmospheric Chemistry and Physics, 2010
The effect of aerosol on clouds poses one of the largest uncertainties in estimating the anthropogenic contribution to climate change. Small human-induced perturbations to cloud characteristics via aerosol pathways can create a change in the top-of ...
I. Koren   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Restricted Boltzmann Machines, Bernoulli Mixtures and Sum-Product Networks: A Matched-Capacity Comparison on Binarized Image Data

open access: yesStats
Generative probabilistic models differ in a fundamental way that is rarely measured directly: some permit exact inference, while others are more expressive but require their likelihood to be estimated.
Mo Ahsan Ahmad, Syed Ejaz Ahmed
doaj   +1 more source

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