Key Points Question How do the alternative statistical tests MaxCombo and difference in restricted mean survival time compare with the log-rank test under nonproportional hazards using data from immuno-oncology trials?
Mukhopadhyay P +6 more
europepmc +2 more sources
Long-Term Impact of D2 Lymphadenectomy during Gastrectomy for Cancer: Individual Patient Data Meta-Analysis and Restricted Mean Survival Time Estimation. [PDF]
Simple Summary Debate exists regarding the effect of D2 vs. D1 lymphadenectomy on long-term oncological outcomes after gastrectomy for cancer. The aim of our individual patient data meta-analysis was to assess the impact of D2 lymphadenectomy on long ...
Aiolfi A +12 more
europepmc +2 more sources
On the empirical choice of the time window for restricted mean survival time. [PDF]
The t‐year mean survival or restricted mean survival time (RMST) has been used as an appealing summary of the survival distribution within a time window [0, t].
Tian L +6 more
europepmc +2 more sources
OBJECTIVES The study sought to demonstrate the statistical and utilitarian properties of restricted mean survival time (RMST) and restricted mean time lost (RMTL) for assessing treatments for heart failure (HF) with reduced ejection fraction ...
C. Perego +10 more
semanticscholar +3 more sources
Key Points Question Is restricted mean survival time (RMST) analysis feasible to translate comparative cardiovascular and kidney outcomes of sodium-glucose cotransporter-2 inhibitor (SGLT2i) vs dipeptidyl peptidase-4 inhibitor (DPP4i) therapy in routine ...
Peng ZY +5 more
europepmc +2 more sources
Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome [PDF]
BackgroundDesigns and analyses of clinical trials with a time-to-event outcome almost invariably rely on the hazard ratio to estimate the treatment effect and implicitly, therefore, on the proportional hazards assumption.
P. Royston, M. Parmar
semanticscholar +3 more sources
Analysis of the Single Ventricle Reconstruction Trial Using Restricted Mean Survival Time and Shunt Type Received [PDF]
Stephen J. Dolgner +2 more
doaj +2 more sources
Clinician's Approach to Advanced Statistical Methods: Win Ratios, Restricted Mean Survival Time, Responder Analyses, and Standardized Mean Differences. [PDF]
Lane M, Miao T, Turgeon RD.
europepmc +2 more sources
Statistical Considerations for Sequential Analysis of the Restricted Mean Survival Time for Randomized Clinical Trials. [PDF]
Lu Y, Tian L.
europepmc +2 more sources
Background Royston-Parmar flexible parametric survival models (FPMs) can be fitted on either the cause-specific hazards or cumulative incidence scale in the presence of competing risks.
Sarwar I. Mozumder +2 more
doaj +1 more source

