Medical therapy, radiofrequency ablation or cryoballoon ablation as first-line treatment for paroxysmal atrial fibrillation: interpreting efficacy through restricted mean survival time and network meta-analysis [PDF]
Reviews in Cardiovascular Medicine, 2021 When multiple treatments are available, network meta-analysis can evaluate data to rank the relative effectiveness. We applied this approach to first-line treatments for paroxysmal atrial fibrillation (medical therapy, radiofrequency ablation or ...
Andrea Messori +3 more
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, 2023 The restricted mean survival time (RMST) difference and the restricted mean time lost (RMTL) ratio for outcomes.
Ivan Chi Ho Au (12902264) +15 more
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A Brief Overview of Restricted Mean Survival Time Estimators and Associated Variances
Stats, 2020 Restricted Mean Survival Time ( R M S T ) experiences a renaissance and is advocated as a model-free, easy to interpret alternative to proportional hazards regression and hazard rates with implication in causal inference. Estimation of R M S T
Szilárd Nemes +2 more
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Matched design for marginal causal effect on restricted mean survival time in observational studies
Journal of Causal Inference, 2023 Investigating the causal relationship between exposure and time-to-event outcome is an important topic in biomedical research. Previous literature has discussed the potential issues of using hazard ratio (HR) as the marginal causal effect measure due to ...
Lin Zihan, Ni Ai, Lu Bo
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Annals of Intensive Care, 2021 Background Fluid therapy is a cornerstone in the treatment of sepsis. Recently, the guidelines have recommended the combined administration that using crystalloids plus albumin for septic patients, but the optimal timing for albumin combined is still ...
Shiyu Zhou +4 more
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Generalized fiducial inference for the restricted mean survival time
, 2023 The standard modeling approach for time-to-event outcomes subject to censoring is based on the hazard function, with hazard ratios capturing the effect of exposures on the risk of outcome.
Ionut Bebu +5 more
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Frontiers in Oncology, 2021 BackgroundThe combination of immune checkpoint inhibitors (ICIs) and chemotherapy is known to improve overall survival (OS) in patients with extensive-stage small cell lung cancer (ES-SCLC).
Shuang Zhang +5 more
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Methods for Direct Modeling of Restricted Mean Survival Time for General Censoring Mechanisms and Causal Inference [PDF]
, 2017 Restricted mean survival time (RMST) is often of great clinical interest in practice. Several existing methods involve explicitly projecting out patient-specific survival curves using parameters estimated through Cox regression. It is often be preferable
Wang, Xin
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Adjusted empirical likelihood analysis of restricted mean survival time for length-biased data [PDF]
Journal of Mahani Mathematical ResearchThe Restricted Mean Survival Time (RMST) serves as a valuable and extensively utilized metric in clinical trials. However, its application becomes intricate when dealing with data affected by length-biased sampling, rendering traditional inference ...
Zahra Mohammadian, Arezoo Habibi
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Definition and Estimation of Covariate Effect Types in the Context of Treatment Effectiveness
Mathematics, 2020 In some clinical studies, assessing covariate effect types indicating whether a covariate is predictive and/or prognostic is of interest, in addition to the study endpoint. Recently, for a case with a binary outcome, Chiba (Clinical Trials, 2019; 16: 237–
Yasutaka Chiba
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