Results 101 to 110 of about 1,391,894 (226)

DNA sequence repeats identify numerous Type I restriction-modification systems that are potential epigenetic regulators controlling phase-variable regulons; phasevarions

, 2020
Over recent years several examples of randomly switching methyltransferases, associated with Type III restriction‐modification (R‐M) systems, have been described in pathogenic bacteria.
Yang, Long, Zhou, Yaoqi, Guo, Chengying, Atack, John M, Jennings, Michael P   +4 more
core   +1 more source

Effect of Dietary Restriction on Muscle Performance in Drosophila [PDF]

, 2011
Dietary restriction (DR) can extend the lifespan in various organisms and is thought to present potential benefits in human. However, it is still a controversial issue now among scientists due to lack of strong supportive evidence in human.
Hsu, Pin-Chia
core   +2 more sources

The Restriction Activity Investigation of Rv2528c, an Mrr-like Modification-Dependent Restriction Endonuclease from Mycobacterium tuberculosis

Microorganisms
Mycobacterium tuberculosis (Mtb), as a typical intracellular pathogen, possesses several putative restriction–modification (R-M) systems, which restrict exogenous DNA’s entry, such as bacterial phage infection.
Tong Liu, Wei Wei, Mingyan Xu, Qi Ren, Meikun Liu, Xuemei Pan, Fumin Feng, Tiesheng Han, Lixia Gou   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The structural basis of differential DNA sequence recognition by restriction–modification controller proteins [PDF]

, 2012
McGeehan, John, Thresh, Sarah, Kneale, Geoff, Ball, Neil J., Streeter, Simon   +4 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Type I restriction-modification system and its resistance in electroporation efficiency in Flavobacterium columnare

, 2012
Flavobacterium columnare, the causative agent of columnaris disease, infects freshwater fish worldwide. However, the pathogenicity of this bacterium is poorly understood due possibly to the lack of an efficient in-frame knockout technique.
Huang, B., Zhang, L. Q., Liu, Z. X., Nie, P., Li, N., Zhang, J., Zhang, S. H., Nie, P (reprint author), Chinese Acad Sci, Stare Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Hubei Province, Peoples R China.   +7 more
core   +1 more source

Molecular cloning and physical mapping of murine cytomegalovirus DNA [PDF]

, 1983
Murine cytomegalovirus (MCMV) Smith strain DNA is cleaved by restriction endonuclease HindIII into 16 fragments, ranging in size from 0.64 to 22.25 megadaltons.
Ebeling, Angelika, Koszinowski, Ulrich H., Knust, Elisabeth, Keil, Günther M.   +3 more
core   +1 more source

Restriction of the growth of T7-like phages by plasmid prophage P1

Фактори експериментальної еволюції організмів, 2014
Aims. Considerable part of T7 phage genome is responsible for interaction with the bacterial host, primarily for the avoidance of action of protective systems of cells, the restriction-modification complexes.
I. V. Faidiuk
doaj  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source