The extremophile Picrophilus torridus carries a DNA adenine methylase M.PtoI that is part of a Type I restriction-modification system [PDF]
Frontiers in Microbiology, 2023 DNA methylation events mediated by orphan methyltransferases modulate various cellular processes like replication, repair and transcription. Bacteria and archaea also harbor DNA methyltransferases that are part of restriction-modification systems, which ...
Pallavi Gulati +3 more
doaj +5 more sources
Type II Restriction-Modification System from Gardnerella vaginalis ATCC 14018 [PDF]
Pathogens, 2020 Intensive horizontal gene transfer may generate diversity and heterogeneity within the genus Gardnerella. Restriction-modification (R-M) systems and CRISPR-Cas are the principal defense tools against foreign DNA in bacteria.
Aistė Bulavaitė +3 more
doaj +4 more sources
Type II restriction modification system in Ureaplasma parvum OMC-P162 strain. [PDF]
PLoS ONE, 2018 Ureaplasma parvum serovar 3 strain, OMC-P162, was isolated from the human placenta of a preterm delivery at 26 weeks' gestation. In this study, we sequenced the complete genome of OMC-P162 and compared it with other serovar 3 strains isolated from ...
Heng Ning Wu +8 more
doaj +4 more sources
The DNA Phosphorothioation Restriction-Modification System Influences the Antimicrobial Resistance of Pathogenic Bacteria [PDF]
Microbiology Spectrum, 2023 Bacterial defense barriers, such as DNA methylation-associated restriction-modification (R-M) and the CRISPR-Cas system, play an important role in bacterial antimicrobial resistance (AMR).
Congrui Xu +9 more
doaj +3 more sources
Characterization of the Type I Restriction Modification System Broadly Conserved among Group A Streptococci [PDF]
mSphere, 2021 Although prokaryotic DNA methylation investigations have long focused on immunity against exogenous DNA, it has been recently recognized that DNA methylation impacts gene expression and phase variation in Streptococcus pneumoniae and Streptococcus suis ...
Sruti DebRoy +8 more
doaj +3 more sources
A functional bacteria-derived restriction modification system in the mitochondrion of a heterotrophic protist. [PDF]
PLoS Biology, 2021 The overarching trend in mitochondrial genome evolution is functional streamlining coupled with gene loss. Therefore, gene acquisition by mitochondria is considered to be exceedingly rare.
David S Milner +4 more
doaj +3 more sources
IS-linked movement of a restriction-modification system. [PDF]
PLoS ONE, 2011 Potential mobility of restriction-modification systems has been suggested by evolutionary/bioinformatic analysis of prokaryotic genomes. Here we demonstrate in vivo movement of a restriction-modification system within a genome under a laboratory ...
Noriko Takahashi +4 more
doaj +3 more sources
Uncovering the link between the SpnIII restriction modification system and LuxS in Streptococcus pneumoniae meningitis isolates. [PDF]
Front Cell Infect Microbiol, 2023 Streptococcus pneumoniae is capable of randomly switching their genomic DNA methylation pattern between six distinct bacterial subpopulations (A-F) via recombination of a type 1 restriction-modification locus, spnIII.
Agnew HN +9 more
europepmc +2 more sources
A novel SfaNI-like restriction-modification system in Caldicellulosiruptor extents the genetic engineering toolbox for this genus [PDF]
PLoS ONE, 2022 Caldicellulosiruptor is a genus of thermophilic to hyper-thermophilic microorganisms that express and secrete an arsenal of enzymes degrading lignocellulosic biomasses into fermentable sugars.
Steve Swinnen +7 more
doaj +3 more sources
A novel restrictionâmodification system fromXanthomonas campestrispv. vesicatoria encodes a m4C-methyltransferase and a nonfunctional restriction endonuclease [PDF]
FEMS Microbiology Letters, 2007 A novel restriction-modification (R-M) system, designated as xveIIRM, from chromosomal DNA of the Xanthomonas campestris pv. vesicatoria strain 7-1 (Xcv7-1) was cloned and characterized. The xveIIRM genes involved in this R-M system are aligned in a tail-to-tail orientation and overlapped by 12 base pairs.
Yu-Jen, Yu, Ming-Te, Yang
openaire +3 more sources