Microbiology Spectrum, 2023 Myriad bacterial anti-phage systems have been described and often the mechanism of programmed cell death is invoked for phage inhibition. However, there is little evidence of “suicide” under physiological conditions for these systems. Instead of death to
Laura Fernández-García +6 more
doaj +2 more sources
Genome analysis of Salmonella enterica serovar Typhimurium bacteriophage L, indicator for StySA (StyLT2III) restriction-modification system action. [PDF]
G3 (Bethesda), 2021 Bacteriophage L, a P22-like phage of Salmonella enterica sv Typhimurium LT2, was important for definition of mosaic organization of the lambdoid phage family and for characterization of restriction-modification systems of Salmonella.
Zaworski J +9 more
europepmc +2 more sources
Analysis of a phase-variable restriction modification system of the human gut symbiont Bacteroides fragilis. [PDF]
Nucleic Acids Res, 2020 The genomes of gut Bacteroidales contain numerous invertible regions, many of which contain promoters that dictate phase-variable synthesis of surface molecules such as polysaccharides, fimbriae, and outer surface proteins.
Ben-Assa N +13 more
europepmc +2 more sources
Low-level expression of the Type II restriction-modification system confers potent bacteriophage resistance in Escherichia coli. [PDF]
DNA Res, 2020 Restriction–modification systems (R–M) are one of the antiviral defense tools used by bacteria, and those of the Type II family are composed of a restriction endonuclease (REase) and a DNA methyltransferase (MTase).
Wilkowska K +3 more
europepmc +2 more sources
The Patchy Distribution of Restriction⁻Modification System Genes and the Conservation of Orphan Methyltransferases in Halobacteria. [PDF]
Genes (Basel), 2019 Restriction-modification (RM) systems in Bacteria are implicated in multiple biological roles ranging from defense against parasitic genetic elements, to selfish addiction cassettes, and barriers to gene transfer and lineage homogenization.
Fullmer MS +4 more
europepmc +2 more sources
The Restriction–Modification Systems of Clostridium carboxidivorans P7
Microorganisms, 2023 Clostridium carboxidivorans P7 (DSM 15243) is a bacterium that converts syngas (a mixture of CO, H2, and CO2) into hexanol. An optimized and scaled-up industrial process could therefore provide a renewable source of fuels and chemicals while consuming ...
Patrick Kottenhahn +4 more
doaj +1 more source
Food microbiology, 2021 We previously reported a distinct methylome between the two Shiga toxin-producing Escherichia coli (STEC) O145:H28 strains linked to the 2010 U.S.
M. Carter +7 more
semanticscholar +1 more source
DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes. [PDF]
PLoS Pathog, 2019 DNA methylation is pervasive across all domains of life. In bacteria, the presence of N6-methyladenosine (m6A) has been detected among diverse species, yet the contribution of m6A to the regulation of gene expression is unclear in many organisms. Here we
Nye TM +6 more
europepmc +2 more sources
Multiple restrictionâmodification systems are present in rumen treponemes [PDF]
FEMS Microbiology Letters, 2005 Type II restriction endonucleases were purified by heparin-sepharose followed by ion chromatography from Treponema strains. The results indicate that in addition to frequently cutting GATC-specific restriction enzymes, the tested strains also possess rarely cutting endonucleases.
Maria, Piknova +2 more
openaire +2 more sources
Nucleic Acids Research, 2021 Restriction-modification (R-M) systems represent a first line of defense against invasive DNAs, such as bacteriophage DNAs, and are widespread among bacteria and archaea.
A. Negri +6 more
semanticscholar +1 more source