Results 51 to 60 of about 18,327,370 (242)

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

BsuMI regulates DNA transformation in Bacillus subtilis besides the defense system and the constructed strain with BsuMI-absence is applicable as a universal transformation platform for wild-type Bacillus

Microbial Cell Factories
Background To effectively introduce plasmids into Bacillus species and conduct genetic manipulations in Bacillus chassis strains, it is essential to optimize transformation methods.
Zhao Xingya, Fu Xiaoping, Zhen Jie, Yang Jun, Zheng Hongchen, Bai Wenqin, Song Hui   +6 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Fourier restriction to polynomial curves I: a geometric inequality [PDF]

, 2010
We prove a Fourier restriction result for general polynomial curves in Rd. Measuring the Fourier restriction with respect to the affine arclength measure of the curve, we obtain a universal estimate for the class of all polynomial curves of bounded ...
Wright, James, Wright, J., null Spyridon Dendrinos, null James Wright, Dendrinos, Spyridon, Dendrinos, S.   +5 more
core   +1 more source

Restriction-modification systems of M. gallisepticum S6.

, 2022
Arrows represent the ORFs; grey, blue, green, and orange colors indicate genes hsdC (controller protein), hsdM (methyltransferase), hsdS (specificity subunit), and hsdR (restriction subunit), respectively. Ori–origin of replication.
Vadim M. Govorun (213423), Alexander A. Arzamasov (14160029), Daria V. Evsyutina (9096071), Valentina G. Ladygina (9096068), Gleb Y. Fisunov (213389), Daria S. Matyushkina (8783387), Irina A. Garanina (14160032), Tatiana A. Semashko (9645302), Olga V. Pobeguts (8497305)   +8 more
core   +1 more source

Comparative analysis of Borrelia’s Defence mechanisms and their impact on genetic manipulation of low-passage isolates of Borrelia afzelii and Borrelia garinii

Current Research in Microbial Sciences
Borrelia, a highly prevalent tick-borne pathogen, has a genome with a linear chromosome and numerous linear and circular plasmids. There are three groups of Borrelia: Lyme borreliosis, relapsing fever, and Echidna-reptile. In Europe, Borrelia afzelii and
Margarida Ruivo, Anna-Margarita Schötta, Theresa Stelzer, Michael Reiter, Michiel Wijnveld   +4 more
doaj   +1 more source

MamA essentiality in Mycobacterium smegmatis is explained by the presence of an apparent cognate restriction endonuclease

BMC Research Notes, 2020
Objective Restriction-Modification (R-M) systems are ubiquitous in bacteria and were considered for years as rudimentary immune systems that protect bacterial cells from foreign DNA.
Samantha E. Randall, Maria Carla Martini, Ying Zhou, Samantha R. Joubran, Scarlet S. Shell   +4 more
doaj   +1 more source

A DNA phosphorothioation-based Dnd defense system provides resistance against various phages and is compatible with the Ssp defense system

mBio, 2023
DndABCDE-catalyzed DNA phosphorothioation (PT), in which the nonbridging oxygen is swapped with a sulfur atom, was first identified in the bacterial genome.
Susu Jiang, Ke Chen, Yingying Wang, Yueying Zhang, Yaru Tang, Wanqiu Huang, Xiaolin Xiong, Shi Chen, Chao Chen, Lianrong Wang   +9 more
doaj   +1 more source

Temporal dynamics of methyltransferase and restriction endonuclease accumulation in individual cells after introducing a restriction-modification system. [PDF]

Nucleic Acids Res, 2016
© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. Type II restriction-modification (R-M) systems encode a restriction endonuclease that cleaves DNA at specific sites, and a methyltransferase that modifies ...
Morozova N, Sabantsev A, Bogdanova E, Fedorova Y, Maikova A, Vedyaykin A, Rodic A, Djordjevic M, Khodorkovskii M, Severinov K.   +9 more
europepmc   +2 more sources