Results 71 to 80 of about 1,391,894 (226)

BsuMI regulates DNA transformation in Bacillus subtilis besides the defense system and the constructed strain with BsuMI-absence is applicable as a universal transformation platform for wild-type Bacillus

Microbial Cell Factories
Background To effectively introduce plasmids into Bacillus species and conduct genetic manipulations in Bacillus chassis strains, it is essential to optimize transformation methods.
Zhao Xingya, Fu Xiaoping, Zhen Jie, Yang Jun, Zheng Hongchen, Bai Wenqin, Song Hui   +6 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1 [PDF]

, 2013
SAMHD1 is a host restriction factor that blocks the ability of lentiviruses such as HIV-1 to undergo reverse transcription in myeloid cells and resting T-cells. This restriction is alleviated by expression of the lentiviral accessory proteins Vpx and Vpr
Emerman, M, Chuanping Wang, Emerman, Michael, Jinwoo Ahn, Jennifer Mehrens (434943), Jacek Skowronski, Michael Emerman, Oliver I. Fregoso (434941), Wang, C, Jinwoo Ahn (140668), Ahn, Jinwoo, Oliver I Fregoso, Fregoso, Oliver I, Skowronski, Jacek, Skowronski, J, Ahn, J, Wang, Chuanping, Michael Emerman (12304), Fregoso, OI, Jennifer Mehrens, Mehrens, J, Mehrens, Jennifer, Chuanping Wang (434942), Jacek Skowronski (62180)   +23 more
core   +2 more sources

Restriction and modification of deoxyarchaeosine (dG+)-containing phage 9 g DNA

Scientific Reports, 2017
E. coli phage 9 g contains the modified base deoxyarchaeosine (dG+) in its genome. The phage encodes its own primase, DNA ligase, DNA polymerase, and enzymes necessary to synthesize and incorporate dG+.
Rebecca Tsai, Ivan R. Corrêa, Michael Y. Xu, Shuang-yong Xu   +3 more
doaj   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

The LspC3–41I restriction-modification system is the major determinant for genetic manipulations of Lysinibacillus sphaericus C3–41

BMC Microbiology, 2017
Background Lysinibacillus sphaericus has been widely used in integrated mosquito control program and it is one of the minority bacterial species unable to metabolize carbohydrates.
Pan Fu, Yong Ge, Yiming Wu, Ni Zhao, Zhiming Yuan, Xiaomin Hu   +5 more
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Restriction Endonucleases and Modification Methylases

, 1993
Restriction endonucleases and modification methylases offer excellent systems for studying protein-DNA interactions. The past year has seen the experimental verification of some aspects of the catalytic mechanisms of both types of enzyme.
Anderson, J. E.
core   +1 more source

A whole genome screen for HIV restriction factors [PDF]

, 2011
Background Upon cellular entry retroviruses must avoid innate restriction factors produced by the host cell. For human immunodeficiency virus (HIV) human restriction factors, APOBEC3 (apolipoprotein-B-mRNA-editing-enzyme), p21 and tetherin are well ...
Dittmar Matthias T, Borgdorff Viola, Matthias T Dittmar, Kelly M Cheney, Áine McKnight, Borgdorff, V, Liu, L, Beach, DH, Pade Corinna, Dreja, H, McKnight, A, Pade, C, Cheney, KM, Dreja Hanna, Nidia MM Oliveira, Bergin, A-MH, Bishop, CL, Bergin Ann-Marie H, Beach David H, Cheney Kelly M, Cleo L Bishop, Dittmar, MT, Bishop Cleo L, Liu Li, David H Beach, Hanna Dreja, Li Liu, Ann-Marie H Bergin, Oliveira, NMM, McKnight Áine, Oliveira Nidia MM, Viola Borgdorff, Corinna Pade   +32 more
core   +8 more sources