Results 1 to 10 of about 145,931 (267)
An Inducible Microbacterium Prophage vB_MoxS-R1 Represents a Novel Lineage of Siphovirus
Viruses, 2022 Lytic and lysogenic infections are the main strategies used by viruses to interact with microbial hosts. The genetic information of prophages provides insights into the nature of phages and their potential influences on hosts.
Hongrui Zheng +6 more
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Dynamics and Conformations of a Full-Length CRESS-DNA Replicase
Viruses, 2023 Circular Rep-encoding single-stranded DNA (CRESS-DNA) viruses encode for a Replicase (Rep) that is essential for viral replication. Rep is a helicase with three domains: an endonuclease, an oligomeric, and an ATPase domain (ED, OD, and AD).
Elvira Tarasova, Reza Khayat
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Mutational Effects of Mobile Introns on the Mitochondrial Genomes of Metschnikowia Yeasts
Frontiers in Genetics, 2021 It has been argued that DNA repair by homologous recombination in the context of endonuclease-mediated cleavage can cause mutations. To better understand this phenomenon, we examined homologous recombination following endonuclease cleavage in a native ...
Scout R. L. Thompson +3 more
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Biochemistry (Moscow), 2009 Nicking endonucleases are a new type of enzymes. Like restriction endonucleases, they recognize short specific DNA sequence and cleave DNA at a fixed position relatively to the recognition sequence. However, unlike restriction endonucleases, nicking endonucleases cleave only one predetermined DNA strand.
Zheleznaya, L. A. +5 more
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Acta Biochimica et Biophysica Sinica, 2022 Prokaryotic Argonaute (pAgo) nucleases with precise DNA cleavage activity show great potential for gene manipulation. Extensive biochemical studies have revealed that recognition of guides with different 5′ groups by Ago is important for biocatalysis ...
Sun Yingying +6 more
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Remdesivir—Bringing Hope for COVID-19 Treatment
Scientia Pharmaceutica, 2020 At the beginning of 2020, the world was swept with a wave of a new coronavirus disease, named COVID-19 by the World Health Organization (WHO 2). The causative agent of this infection is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 ...
Naser F. Al-Tannak +2 more
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Human MUS81: A Fence-Sitter in Cancer
Frontiers in Cell and Developmental Biology, 2021 MUS81 complex, exhibiting endonuclease activity on specific DNA structures, plays an influential part in DNA repair. Research has proved that MUS81 is dispensable for embryonic development and cell viability in mammals.
Sisi Chen +7 more
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Frontiers in Microbiology, 2020 Influenza virus RNA-dependent RNA polymerase (vRdRp) does not have capping activity and relies on the capped RNAs produced by the host RNA polymerase II (RNAPII).
Ao Hu +10 more
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A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay
eLife, 2020 EDC4 is a core component of processing (P)-bodies that binds the DCP2 decapping enzyme and stimulates mRNA decay. EDC4 also interacts with mammalian MARF1, a recently identified endoribonuclease that promotes oogenesis and contains a number of RNA ...
William R Brothers +3 more
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Indonesian Journal of Biotechnology, 2023 Chili (Capsicum annuum L.) is a highly valued vegetable, renowned for its unique taste and aroma. However, chili production faces challenges in meeting the high demand due to infections caused by pathogens such as ChiVMV (potyvirus).
Josefanny Tham +5 more
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