Results 91 to 100 of about 1,050,756 (279)

The role of the restriction-modification system of Clostridium pasteurianum on its electro-transformation [PDF]

, 2013
Dissertação de mestrado em BioengenhariaClostridium pasteurianum is a Gram-positive and anaerobic bacterium with a great biotechnological potential. It is one of the few microorganisms capable of hydrolyzing glycerol to produce solvents as ethanol and ...
Magalhães, Carla Isabel Pereira
core  

Compensation for Uneven Surfaces When Building Laser Deposited Structures [PDF]

, 2004
Direct Laser Deposition (DLD) is a blown-powder laser deposition process that can be used to quickly produce, modify or repair fully-dense metallic parts by a layered manufacturing method. However, uneven substrate surfaces often cause variation in the
Fearon, E., Watkins, K. G.
core   +1 more source

MspGI Restriction–Modification System and Its Flanking Genes of Microbacterium sp. Gd 4-13

Biology and Life Sciences Forum
Bacteria have defense systems against the penetration of foreign DNA (phages and plasmids). Some defense systems protect bacteria from phage penetration into the cell, while others block phage replication. Antiphage defense systems are often located next
Alfiya K. Yunusova, Elena V. Spirina, Valeriya N. Antipova, Rimma I. Artyukh   +3 more
doaj   +1 more source

A DNA phosphorothioation-based Dnd defense system provides resistance against various phages and is compatible with the Ssp defense system

mBio, 2023
DndABCDE-catalyzed DNA phosphorothioation (PT), in which the nonbridging oxygen is swapped with a sulfur atom, was first identified in the bacterial genome.
Susu Jiang, Ke Chen, Yingying Wang, Yueying Zhang, Yaru Tang, Wanqiu Huang, Xiaolin Xiong, Shi Chen, Chao Chen, Lianrong Wang   +9 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Characterization of a restriction modification system from the commensal Escherichia coli strain A0 34/86 (O83:K24:H31)

BMC Microbiology, 2008
Background Type I restriction-modification (R-M) systems are the most complex restriction enzymes discovered to date. Recent years have witnessed a renaissance of interest in R-M enzymes Type I.
Ryu Junichi, Weiserová Marie
doaj   +1 more source

MamA essentiality in Mycobacterium smegmatis is explained by the presence of an apparent cognate restriction endonuclease

BMC Research Notes, 2020
Objective Restriction-Modification (R-M) systems are ubiquitous in bacteria and were considered for years as rudimentary immune systems that protect bacterial cells from foreign DNA.
Samantha E. Randall, Maria Carla Martini, Ying Zhou, Samantha R. Joubran, Scarlet S. Shell   +4 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

The DNA Methylome of the Hyperthermoacidophilic Crenarchaeon Sulfolobus acidocaldarius

Frontiers in Microbiology, 2018
DNA methylation is the most common epigenetic modification observed in the genomic DNA (gDNA) of prokaryotes and eukaryotes. Methylated nucleobases, N6-methyl-adenine (m6A), N4-methyl-cytosine (m4C), and 5-methyl-cytosine (m5C), detected on gDNA ...
Mohea Couturier, Ann-Christin Lindås
doaj   +1 more source