Results 101 to 110 of about 18,457,999 (286)

Structure and evolution of theXcylrestriction-modification system [PDF]

open access: yesNucleic Acids Research, 1992
The XcyI restriction-modification system from Xanthomonas cyanopsidis recognizes the sequence, CCCGGG. The XcyI endonuclease and methylase genes have been cloned and sequenced and were found to be aligned in a head to tail orientation with the methylase preceding and overlapping the endonuclease by one base pair. The nucleotide sequence codes for an N4
B E, Withers, L A, Ambroso, J C, Dunbar
openaire   +2 more sources

Absence in Bacillus subtilis and Staphylococcus aureus of the sequence-specific deoxyribonucleic acid methylation that is conferred in Escherichia coli K-12 by the dam and dcm enzymes [PDF]

open access: yes, 1981
Dreiseikelmann B, Wackernagel W. Absence in Bacillus subtilis and Staphylococcus aureus of the sequence-specific deoxyribonucleic acid methylation that is conferred in Escherichia coli K-12 by the dam and dcm enzymes. Journal of Bacteriology. 1981;147(1):
Dreiseikelmann, Brigitte   +1 more
core  

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Restriction modification systems in archaea: A panoramic outlook

open access: yesHeliyon
Restriction modification (RM) systems are one of the ubiquitous yet primitive defense responses employed by bacteria and archaea with the primary role of safeguarding themselves against invading bacteriophages. Protection of the host occurs by the cleavage of the invading foreign DNA via restriction endonucleases with concomitant methylation of host ...
Pallavi Gulati   +4 more
openaire   +3 more sources

Restriction modification protein subunits increased at peak infection times.

open access: yes, 2012
Bars indicate normalized spectral counts averaged between two technical replicates and lines are optical density measurements taken at each time point. Untreated cells MOI = 0, green bars and lines, infected cells at MOI = 0, maroon bars and lines, and ...
Christophe Fremaux (161090)   +9 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Toxin/antitoxin systems induce persistence and work in concert with restriction/modification systems to inhibit phage

open access: yesMicrobiology Spectrum
Myriad bacterial anti-phage systems have been described and often the mechanism of programmed cell death is invoked for phage inhibition. However, there is little evidence of “suicide” under physiological conditions for these systems. Instead of death to
Laura Fernández-García   +6 more
doaj   +1 more source

ATPase activity of the type IC restriction-modification system EcoR124II.

open access: yes, 1996
We have investigated the ATPase activity of the type IC restriction-modification (R-M) system EcoR124II. As with all type I R-M systems EcoR 124II requires ATP hydrolysis to cut DNA. We determined the KM for ATP to be 10(-5) to 10(-4) M. By measuring ATP
Bickle TA, Dreier J
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

A bacterial defense system targeting modified cytosine of phage genomic DNA

open access: yesNature Communications
The evolutionary arms race between bacteria and phages drives the development of bacterial antiviral defense systems and phage counter-defense strategies.
Rui Liu   +6 more
doaj   +1 more source

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