Results 61 to 70 of about 1,050,756 (279)

Impact of target site distribution for Type I restriction enzymes on the evolution of methicillin-resistant Staphylococcus aureus (MRSA) populations. [PDF]

, 2013
A limited number of Methicillin-resistant Staphylococcus aureus (MRSA) clones are responsible for MRSA infections worldwide, and those of different lineages carry unique Type I restriction-modification (RM) variants.
Abadjieva, Augoustinos S. Stephanou, Bickle, Bron, Budroni, Calisto, Cerdeño-Tárraga, Charpentier, Chen, Cockfield, Corvaglia, David T.F. Dryden, DeLeo, Diep, Dryden, Dryden, Dybvig, Ellrott, Fang, Fey, Furuta, Gao, Gareth A. Roberts, Gelfand, Gill, Harris, International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements, Jodi A. Lindsay, John H. White, Kai Chen, Karlin, Kasarjian, Kennaway, Kennaway, Kim, Knight, Krüger, Kuroda, Laurie P. Cooper, Limbago, Lindsay, Löfblom, McCarthy, McCarthy, McCarthy, McCarthy, McDougal, Monk, Morgan, Patrick J. Houston, Roberts, Roberts, Robinson, Rocha, Schouler, Sharp, Stefani, Sturrock, Taylor, Tenover, Tock, Tsuru, Waldron, Xu, Zhang   +64 more
core   +1 more source

Enhanced Fusobacterium nucleatum Genetics Using Host DNA Methyltransferases To Bypass Restriction-Modification Systems

Journal of Bacteriology, 2022
Fusobacterium nucleatum is an oral opportunistic pathogen associated with diseases that include cancer and preterm birth. Our understanding of how this bacterium modulates human disease has been hindered by a lack of genetic systems.
Ariana Umaña, Tam T. D. Nguyen, Blake E. Sanders, K. Williams, Bryce Wozniak, D. J. Slade   +5 more
semanticscholar   +1 more source

Targeted genome modifications in soybean with CRISPR/Cas9 [PDF]

, 2015
Background: The ability to selectively alter genomic DNA sequences in vivo is a powerful tool for basic and applied research. The CRISPR/Cas9 system precisely mutates DNA sequences in a number of organisms.
Jacobs, Thomas, LaFayette, Peter R, Parrott, Wayne A, Schmitz, Robert J   +3 more
core   +2 more sources

Adaptive Tracking Control of an Electro-Pneumatic Clutch Actuator [PDF]

Modeling, Identification and Control, 2003
This paper deals with the application of a simple adaptive algorithm for robust tracking control of an electro-pneumatic clutch actuator with output feedback.
Glenn-Ole Kaasa, Masanori Takahashi
doaj   +1 more source

Removal of a frameshift between the hsdM and hsdS genes of the EcoKI Type IA DNA restriction and modification system produces a new type of system and links the different families of Type I systems [PDF]

, 2012
The EcoKI DNA methyltransferase is a trimeric protein comprised of two modification subunits (M) and one sequence specificity subunit (S). This enzyme forms the core of the EcoKI restriction/modification (RM) enzyme. The 3′ end of the gene encoding the M
Blakely, Garry W, Chen, Kai, Cooper, Laurie P, Dryden, David T F, Roberts, Gareth A, White, John H   +5 more
core   +1 more source

The SUMO Ligase Protein Inhibitor of Activated STAT 1 (PIAS1) is a constituent PML-NB protein that contributes to the intrinsic antiviral immune response to herpes simplex virus 1 (HSV-1) [PDF]

, 2016
Aspects of intrinsic antiviral immunity are mediated by promyelocytic leukaemia (PML)-nuclear body (PML-NB) constituent proteins. During herpesvirus infection, these antiviral proteins are independently recruited to nuclear domains that contain infecting
Boutell, Chris, Brown, James R., Charman, Matthew, Conn, Kristen L., Grant, Kyle, McFarlane, Steven, Tong, Lily, Wasson, Peter   +7 more
core   +1 more source

Analysis of the subunit assembly of the type IC restriction-modification enzyme EcoR124I [PDF]

, 1998
Type I restriction-modification (R-M) enzymes are composed of three different subunits, of which HsdS determines DNA specificity, HsdM is responsible for DNA methylation and HsdR is required for restriction.
Dryden, D T F, Firman, K, Janscak, P
core   +2 more sources

Avoidance of recognition sites of restriction-modification systems is a widespread but not universal anti-restriction strategy of prokaryotic viruses

BMC Genomics, 2018
Background Restriction-modification (R-M) systems protect bacteria and archaea from attacks by bacteriophages and archaeal viruses. An R-M system specifically recognizes short sites in foreign DNA and cleaves it, while such sites in the host DNA are ...
I. S. Rusinov, A. S. Ershova, A. S. Karyagina, S. A. Spirin, A. V. Alexeevski   +4 more
doaj   +1 more source

Effect of minimal length uncertainty on the mass-radius relation of white dwarfs

, 2017
Generalized uncertainty relation that carries the imprint of quantum gravity introduces a minimal length scale into the description of space-time. It effectively changes the invariant measure of the phase space through a factor $(1+\beta \mathbf{p}^2 ...
Mathew, Arun, Nandy, Malay K.
core   +1 more source

Genetic Stabilization of the Drug-Resistant PMEN1 Pneumococcus Lineage by Its Distinctive DpnIII Restriction-Modification System

mBio, 2015
The human pathogen Streptococcus pneumoniae (pneumococcus) exhibits a high degree of genomic diversity and plasticity. Isolates with high genomic similarity are grouped into lineages that undergo homologous recombination at variable rates.
Rory A. Eutsey, Evan Powell, Janina Dordel, S. Salter, Tyson A. Clark, J. Korlach, G. Ehrlich, N. Hiller, Eutsey Ra, Powell E, Dordel J, Salter Sj, Clark Ta, J. Korlach, Ehrlich Gd, Hiller, Donald A Morrison, Luisa Hiller   +17 more
semanticscholar   +1 more source