Results 81 to 90 of about 2,984,053 (262)
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source
Comprehensive Review of Human Plasmodium falciparum-Specific CD8+ T Cell Epitopes
Control of malaria is an important global health issue and there is still an urgent need for the development of an effective prophylactic vaccine. Multiple studies have provided strong evidence that Plasmodium falciparum-specific MHC class I-restricted ...
Janna Heide +7 more
doaj +1 more source
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba +11 more
wiley +1 more source
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm +10 more
wiley +1 more source
Este estudo foi realizado para avaliar o desempenho, o controle da manifestação de doenças metabólicas e o rendimento de carcaça de frangos de corte machos submetidos à restrição alimentar no período de 8 a 14 dias de idade.
Helenice Mazzuco +2 more
doaj +1 more source
Calorie restriction is the most effective intervention with prolongevity effects in many of the organisms. Calorie restriction can be considered as the reduction of the intake of energy without reaching malnutrition. The effect of calorie restriction is not only reserved to an extended longevity but also delays the onset and reduces the progression of ...
López-Lluch, Guillermo, Navas, Plácido
openaire +2 more sources
Care home rules to prevent the spread of coronavirus are too strict and not based on science. This could cost lives, says June Andrews.
openaire +2 more sources
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi +4 more
wiley +1 more source
Functional Insights into ANP32A-Dependent Influenza A Virus Polymerase Host Restriction
Host restriction of influenza A virus limits pandemic emergence. The viral RNA polymerase (vPol) is an essential enzyme that must adapt for avian viruses to replicate in humans. Species differences in host ANP32A dictate adaptation: human ANP32A lacks an
Patricia Domingues, Benjamin G. Hale
doaj +1 more source

