Results 91 to 100 of about 347,445 (313)
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
The type IIS restriction enzyme MmeI can cut across a double-strand break. [PDF]
Mol Biol Rep, 2023 Tasnim M, Selph TJ, Olcott J, Hill JT.
europepmc +1 more source
Enzymes by post—restriction enzyme stability [PDF]
Nature Biotechnology, 2000 Jason R. Clark, John B. March
openaire +3 more sources
Cleavage of Simian Virus 40 DNA at a Unique Site by a Bacterial Restriction Enzyme [PDF]
, 1972 John F. Morrow, Paul Berg
openalex +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Association Analysis of miR423 (rs6505162) and miR608 (rs4919510) Polymorphisms with Lung Cancer Risk [PDF]
Journal of Mazandaran University of Medical SciencesBackground and purpose: Lung cancer is one of the deadliest cancers in the world, early detection of lung cancer is one of the biggest challenges in treating this disease and can be very effective in saving patients.
Javad Salehi, Morteza Sadeghi
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Exploration of DPP-IV Inhibitory Peptide Design Rules Assisted by the Deep Learning Pipeline That Identifies the Restriction Enzyme Cutting Site. [PDF]
ACS Omega, 2023 Guan C +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Conversion of barley SNPs into PCR-based markers using dCAPS method
Genetics and Molecular Biology, 2009 Molecular genetic research relies heavily on the ability to detect polymorphisms in DNA. Single nucleotide polymorphisms (SNPs) are the most frequent form of DNA variation in the genome.
Fahimeh Shahinnia +1 more
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