Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Paxilline negative mutants of Penicillium paxilli generated by heterologous and homologous plasmid integration : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Genetics at Massey University, Palmerston North, New Zealand [PDF]
, 1998 Using a monoclonal antibody-based ELISA, 600 pAN7-1 plasmid-tagged mutants of Penicillium paxilli were screened for paxilline accumulation and one paxilline negative mutant, YI-20, was identified (Itoh, unpublished data).
Young, Carolyn Anne
core
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
BMC Bioinformatics, 2010 Background PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction enzyme sites is challenging and cumbersome.
Chang Hsueh-Wei +3 more
doaj +1 more source
Theoretic Insight into CO2 Reduction at Active Sites of Molybdenum and Tungsten Enzymes: a π Interaction between CO2 and Tungsten Bis-Dithiolene Complexes [PDF]
arXiv, 2014 Active sites of molybdenum and tungsten enzymes, particularly mononuclear tungsten formate dehydrogenase (FDH) have been theoretically investigated towards their interaction with CO2. Obvious {\pi} interaction has been found between the 2e reduced metallodithiole moiety and the molecular CO2.
arxiv
The type IIS restriction enzyme MmeI can cut across a double-strand break. [PDF]
Mol Biol Rep, 2023 Tasnim M, Selph TJ, Olcott J, Hill JT.
europepmc +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Sequence analysis of the second internal Transcribed spacer (ITS2) region of rDNA for species identification of trichostrongylus nematodes isolated from domestic livestock in Iran [PDF]
, 2012 Background: Infectivity of herbivores with Trichostrongylus nematodes is widespread in many countries, having a major economic impact on breeding, survivability, and productivity of domestic livestock.
Fasihi Harandi, M. +5 more
core +2 more sources
Exploration of DPP-IV Inhibitory Peptide Design Rules Assisted by the Deep Learning Pipeline That Identifies the Restriction Enzyme Cutting Site. [PDF]
ACS Omega, 2023 Guan C +10 more
europepmc +1 more source
Restriction enzyme cleavage sites surrounding the structural gene for the lipoprotein of the Escherichia coli outer membrane [PDF]
, 1979 K. Nakamura +3 more
openalex +1 more source
Enzymes by post—restriction enzyme stability [PDF]
Nature Biotechnology, 2000 Jason R. Clark, John B. March
openaire +3 more sources