Molecular detection of fluoroquinolone-resistant Neisseria meningitidis by using mismatched PCR-restriction fragment length polymorphism technique. [PDF]
Front Cell Infect Microbiol, 2022 Ota Y, Okada R, Takahashi H, Saito R.
europepmc +1 more source
The mapping and ordering of fragments of SV40 DNA produced by restriction endonucleases [PDF]
, 1974 K. N. Subramanian +3 more
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Genotypic confirmation of a biased phenotypic sex ratio in a dryland moss using restriction fragment length polymorphisms. [PDF]
Appl Plant Sci, 2022 Ekwealor JTB +7 more
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Study of Calpastatin Gene Polymorphism in Holstein Cattle and Buffalo
Scientific Papers Animal Science and Biotechnologies, 2023 In this research for studying genetic polymorphism of calpastatin (CAST) gene as candidate gene for marker-assisted selection in different domestic livestock species, blood samples were collected from 50 Holstein cattle and 40 buffalo randomly.
Soheil Yousefi, Ahani Azari Mojtaba
doaj
Evaluating the Association of Genetic Polymorphism of Cytochrome p450 (CYP2C9*3) in Gastric Cancer Using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). [PDF]
Cureus, 2022 Uthansingh K +4 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
DIABETICO-PROTECTIVE ROLE OF VITAMIN D
Pakistan Journal of Medicine and Dentistry, 2019 Studies worldwide have observed a link between VDR polymorphism and Diabetes Mellitus. Diabetes is a complex disease characterized by insulin deficiency caused by the alterations in the function of pancreatic β-cells, insulin sensitivity and systemic ...
Asif Memon +3 more
doaj
On complexity of restricted fragments of Decision DNNF
Decision DNNF (a.k.a. $\wedge_d$-FBDD) is an important special case of Decomposable Negation Normal Form (DNNF). Decision DNNF admits FPT sized representation of CNFs of bounded \emph{primal} treewidth. However, the complexity of representation for CNFs of bounded \emph{incidence} treewidth is wide open.
Calí, Andrea, Razgon, Igor
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