Results 211 to 220 of about 288,437 (264)
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Telomeric Terminal Restriction Fragment (TRF)
2003Telomeres are protein-DNA structures at the ends of all eukaryotic chromosomes that are maintained by a unique ribonucleoprotein known as telomerase. This highly specialized RNA-dependent DNA polymerase provides a critical solution to the end-replication problem by adding TTAGGG repeats to 3' ends of human chromosomes (1-3). Telomere regulation is both
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Chromosome 13 restriction fragment length polymorphisms
Human Genetics, 1984The gene locus for hereditary retinoblastoma is on human chromosome 13, band q14. With this gene localization in mind, we cloned DNA fragments from this chromosome. Three of the fragments identify restriction fragment length polymorphisms. These three fragments are from the region 13q12-13q22, the chromosome region which contains the retinoblastoma ...
T P, Dryja +3 more
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Immunoglobulin genes in DNA restriction fragments
Biochemistry, 1978We have investigated the organization of immunoglobulin genes in mice. High molecular weight DNA from myelomas and Krebs ascites cells was cleaved with EcoRI restriction endonuclease and fractionated using preparative agarose gel electrophoresis. Each fraction was then hybridized to an immunoglobulin mRNA or a cDNA transcribed from the mRNA.
R, Wilson +3 more
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Restriction fragment length polymorphism
1988In the 1960s, a group of enzymes were discovered in bacteria that could degrade incoming bacteriophage DNA and would ‘restrict’ their establishment in the cell [2,6]. These enzymes, known as restriction enzymes [19], have proved very valuable in modern manipulations of DNA.
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Restriction Fragment Length Polymorphism Typing of Mycobacteria
2003In principle, restriction fragment length polymorphism (RFLP) typing can be applied to strains of all mycobacterial species for which suitable probes have been identified. International consensus has been achieved regarding the methodology of IS6110 RFLP typing of Mycobacterium tuberculosis complex isolates (1) and IS1245 RFLP typing of Mycobacterium ...
van Soolingen, Drivm +2 more
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Integrated Microdevice for DNA Restriction Fragment Analysis
Analytical Chemistry, 1996An integrated monolithic device (8 mm × 10 mm) that performs an automated biochemical procedure is demonstrated. The device mixes a DNA sample with a restriction enzyme in a 0.7-nL reaction chamber and after a digestion period injects the fragments onto a 67-mm-long capillary electrophoresis channel for sizing. Materials are precisely manipulated under
S C, Jacobson, J M, Ramsey
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Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Restriction fragment analysis of somaclones
1991Somaclonal variation is a feature common to all plant regeneration via a tissue culture or ‘callus’ phase [7, 10]. Whether the intention is to maximise variation (for production of variability in plant breeding) or minimise it (to reduce variability in mass propagation systems or transformation studies) it is very important to be able to identify ...
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Monodisperse DNA restriction fragments
Journal of Colloid and Interface Science, 2005Gijsberta H. Koenderink +3 more
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