Results 71 to 80 of about 280,842 (293)

EPIDEMIOLOGICAL SURVEY OF DIFFERENT RABIES VIRUS STRAINS IN IRAN [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 2001
Rabies is widespread in all provinces of Iran. This study presents an investigation by a Polymerase Chain Reaction (PCR) technique for the purpose of rabies diagnosis and also Restriction Fragment Length Polymorphism (RFLP) for determination of the type ...
doaj  

A proof-theoretic semantics for contextual domain restriction

open access: yesJournal of Language Modelling, 2015
The paper presents a proof-theoretic semantics account of contextual domain restriction for quantified sentences in a fragment of English. First, the technique is exemplified in the more familiar first-order logic, and in its restricted quantification ...
Nissim Francez
doaj   +1 more source

Comparative Application of Terminal Restriction Fragment Analysis Tools to Large-Scale Genomic Assays. [PDF]

open access: yesInt J Mol Sci, 2023
Abdulkina LR   +5 more
europepmc   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Identification of Burkholderia mallei Isolates with Polymerase Chain Reaction-Restriction Fragment Length Polymorphism. [PDF]

open access: yesArch Razi Inst, 2023
Abnaroodheleh F   +4 more
europepmc   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Molecular typing of canine parvovirus type 2 by VP2 gene sequencing and restriction fragment length polymorphism in affected dogs from Egypt. [PDF]

open access: yesFront Microbiol, 2023
Magouz A   +8 more
europepmc   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

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