Results 231 to 240 of about 620,532 (331)

Longitudinal analysis of body weight reveals homeostatic and adaptive traits linked to lifespan in diversity outbred mice. [PDF]

Nat Commun
Prateek GV, Chen Z, Wright K, Di Francesco A, Jojic V, Churchill GA, Raj A.   +6 more
europepmc   +1 more source

Long-Range Mapping of the Streptococcus agalactiae Phylogenetic Lineage Restriction Digest Pattern Type III-3 Reveals Clustering of Virulence Genes

, 2002
John F. Bohnsack, April Whiting, Russell D. Bradford, Brenna K. Van Frank, Shinji Takahashi, Elisabeth E. Adderson   +5 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Generative artificial intelligence in dementia care: a scoping review protocol on nursing roles, experiences and ethical perspectives. [PDF]

BMJ Open
Chen YC, Nieh HC, Chen HC, Chen JC, Chang MY, Wu PO.   +5 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Bridging the gap between human behaviour and animal welfare: A study on human behaviour change and body condition scoring of suckler cows. [PDF]

Anim Welf
Jessiman L, Naydani CJ, Rutherford KM, Turner SP.   +3 more
europepmc   +1 more source

Methodological Characterization and Mapping of Artificial Intelligence Pipelines for Fetal Growth Restriction Prediction: A Scoping Review

jingtao
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Benchmarking alignment strategies for Hi-C reads in metagenomic Hi-C data. [PDF]

Genome Biol
Wang Y, Zuo W, Huang J, Sun F, Du Y.
europepmc   +1 more source

Additional file 1: of De novo SNP discovery and genetic linkage mapping in poplar using restriction site associated DNA and whole-genome sequencing technologies

, 2016
Mohaddeseh Mousavi, Chunfa Tong, Fenxiang Liu, Shentong Tao, Jiyan Wu, Huogen Li, Jisen Shi   +6 more
openalex   +1 more source