Results 261 to 270 of about 3,801,363 (334)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Barriers and Facilitators to Patient Acceptance of Artificial Intelligence in Health Care: Systematic Review. [PDF]

J Med Internet Res
Shi H, Huang J, Yang J, Han M.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Controllable Chemical Vapor Deposition Synthesis and Second-Harmonic Generation of Rhombohedral Cr₂S₃. [PDF]

Nanomaterials (Basel)
Zhang D, Li P, Liu S, Ye Q, Chen Y.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Carbon Dioxide Insufflation for Assessment of Pericardial Adhesions and Informed Decision-Making for Percutaneous Epicardial Access in a Patient With Prior Cardiac Surgery. [PDF]

J Arrhythm
Kasai Y, Kitai T, Morita J, Hama G, Yamashita K.   +4 more
europepmc   +1 more source

Local triviality of the restriction map for embeddings

Commentarii Mathematici Helvetici, 1960
openaire   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Comparative Analysis of Magnetic Resonance Spectroscopy and Post-contrast Magnetic Resonance Imaging in the Evaluation of Intracranial Ring-Enhancing Lesions. [PDF]

Cureus
Bode R, Kumar A, Sarkar KN, Singh BN, Ruprela V, Ruprela H, Nihal R, Shandilya D, Ganjeer R, Anil J.   +9 more
europepmc   +1 more source

Immune checkpoint inhibitor-associated severe hyponatremia: evidence mapping of SIADH-like phenotypes and endocrine immune-related adverse events. [PDF]

Endocr Connect
Guo F, Han S, Xue Z, Chen W, Gou Y.
europepmc   +1 more source