Results 271 to 280 of about 620,532 (331)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The science and legacies of Ronald Phillips: A brief perspective. [PDF]

Plant Genome
Flavell RB.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Methods for telomere length measurement: an update on current technologies and emerging approaches. [PDF]

Front Mol Biosci
Makarova JA, Belova UD, Zvereva MI, Shkurnikov MY, Tonevitsky AG.   +4 more
europepmc   +1 more source

Restriction Enzyme Mapping Method Corrected

The American Biology Teacher, 1991
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Enhanced rice breeding with GLR1_CAPS marker for glabrous hull selection. [PDF]

BMC Plant Biol
Park JR, Seo J, Lee CM, Ji H, Jeong OY, Park HS.   +5 more
europepmc   +1 more source

The missing data problem in population genomics and statistical methods to address them. [PDF]

G3 (Bethesda)
Sethuraman A.
europepmc   +1 more source

Analysis of lifespan across diversity outbred mouse studies identifies multiple longevity-associated loci. [PDF]

Genetics
Mullis MN, Wright KM, Raj A, Gatti DM, Reifsnyder PC, Flurkey K, Archer JR, Robinson L, Di Francesco A, Svenson KL, Korstanje R, Harrison DE, Ruby JG, Churchill GA.   +13 more
europepmc   +1 more source

Reading between the Chains: Surface Mapping and Druggable Pockets on the Biological Assemblies of DENV-2's Protein E. [PDF]

ACS Omega
Leite PTTF, Fernandes PO, Lacerda PS, Chagas MA, Castilho MS, Rocha WR, Moraes AH, Maltarollo VG.   +7 more
europepmc   +1 more source