Results 61 to 70 of about 610,827 (332)

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yesFEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic   +2 more
wiley   +1 more source

Localized Expression of Cathepsin B-like Sequences from Root Nodules of Pea (Pisum sativum)

open access: yesMolecular Plant-Microbe Interactions, 2000
Cathepsin B is an ancient family of eukaryotic cysteine proteases. We describe PsCat1, a plant cathepsin B-like transcript, identified as an expressed sequence in Rhizobium-induced, nitrogen-fixing root nodules of pea.
Jason L. Vincent   +2 more
doaj   +1 more source

Modular Invariants, Graphs and $\alpha$-Induction for Nets of Subfactors I

open access: yes, 1998
We analyze the induction and restriction of sectors for nets of subfactors defined by Longo and Rehren. Picking a local subfactor we derive a formula which specifies the structure of the induced sectors in terms of the original DHR sectors of the smaller
Böckenhauer, J., Evans, D. E.
core   +4 more sources

The Torelli map restricted to the hyperelliptic locus [PDF]

open access: yesTransactions of the American Mathematical Society, Series B, 2021
Let g ≥ 2 g \geq 2 and let the Torelli map denote the map sending a genus g g curve to its principally polarized Jacobian. We show that the restriction of the Torelli map to the hyperelliptic locus is an immersion in characteristic not 2 2 . In characteristic 2 2
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

The nontriviality of the restriction map in the cohomology of groups. [PDF]

open access: yesProceedings of the American Mathematical Society, 1960
An unpublished result2 of B. Mazur states that if ir is any nontrivial finite group then there is an i> 0 such that Hi(Qr, Z) $0. It is, course, trivial that Hi(ir, A) #0 for some ir-module A. The point of Mazur's theorem is that we can even take A = Z, the ring of integers with trivial ir-action. Mazur's proof of this theorem is geometric. It involves
openaire   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Protocol for mapping the three-dimensional organization of dinoflagellate genomes

open access: yesSTAR Protocols
Summary: Dinoflagellate genomes often are very large and difficult to assemble, which has until recently precluded their analysis with modern functional genomic tools.
Georgi K. Marinov   +3 more
doaj   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Increased sleep depth in developing neural networks: new insights from sleep restriction in children

open access: yesFrontiers in Human Neuroscience, 2016
Brain networks respond to sleep deprivation or restriction with increased sleep depth, which is quantified as slow-wave activity (SWA) in the sleep electroencephalogram (EEG).
Salome Kurth   +11 more
doaj   +1 more source

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