Results 211 to 220 of about 16,738 (270)

Electrocardiographic Correlates of Myocardial Remodeling After Cardiac Resynchronization Therapy

Pacing and Clinical Electrophysiology, EarlyView.
Christian Toquica, Amulya Gupta, Tucker Morey, Christopher J. Harvey, Seth H. Sheldon, Madhu Reddy, Amit Noheria   +6 more
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Clinical profile of restrictive cardiomyopathy in children at a South Indian tertiary care cardiac center: A retrospective three decade experience. [PDF]

Ann Pediatr Cardiol
Kawoos GM, Gopalakrishnan A, Krishnamoorthy KM, Sasidharan B, Kurup HKN, Sarma PS, Namboodiri N, Sivadasanpillai H.   +7 more
europepmc   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

Biallelic potential disease-causing missense variants in TAF1A in two siblings with infantile restrictive cardiomyopathy. [PDF]

Eur J Med Genet
Jiang N, Xu W, Abdelhakim A, Matveyenko A, Szabolcs M, Copeland WC, Disco M, Iglesias A, Lee TM, Naini A, Ganapathi M.   +10 more
europepmc   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source

The bird hunting story: constrictive pericarditis and restrictive cardiomyopathy. [PDF]

Indian J Thorac Cardiovasc Surg
Subramaniam KG, Sharma D.
europepmc   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat, Jaffar Al‐Sheikhli, Andrew M. Blanks, Joseph Mayer, Nicolas Lellouche, Tarvinder Dhanjal, Christopher O'Shea   +6 more
wiley   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

The Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue, Rajesh Katare, Jeremiah Deng, Daniel Alencar Da Costa, Patrick Manning   +4 more
wiley   +1 more source

Ventilatory efficiency: Physiological modelling and mechanistic validation

The Journal of Physiology, EarlyView.
Abstract figure legend From post‐threshold ventilatory linearization to ceiling‐normalized efficiency – conceptual framework underlying ηV̇E$\eta {{\dot{V}}_{\mathrm{E}}}$ Conventional V̇E${{\dot{V}}_{\mathrm{E}}}$–V̇CO2${{\dot{V}}_{{\mathrm{C}}{{{\mathrm{O}}}_2}}}$ slopes are typically derived under submaximal conditions and may become physiologically
Paulo T Muller, Beate Stubbe, Till Ittermann, Erlandson S Ferreira, J A Neder, Ralf Ewert   +5 more
wiley   +1 more source