Results 221 to 230 of about 16,738 (270)

Kinematic‐calcium loops unravel impaired excitation–contraction coupling in MELAS‐affected cardioids

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Representation of kinematic and calcium transient loop with respect to traditional time coplotting. Abstract Impaired Ca2+ handling, and in particular leakage from the sarcoplasmic reticulum, is a critical mechanism in metabolic diseases affecting the heart.
Margherita Burattini   +7 more
wiley   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato   +3 more
wiley   +1 more source

Impaired Relaxation in Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Pathogenic <i>TNNI3</i> Mutation of Pediatric Restrictive Cardiomyopathy. [PDF]

open access: yesJ Am Heart Assoc
Wang R   +16 more
europepmc   +1 more source

Gene correction and overexpression of TNNI3 improve impaired relaxation in engineered heart tissue model of pediatric restrictive cardiomyopathy. [PDF]

open access: yesDev Growth Differ
Hasegawa M   +13 more
europepmc   +1 more source

Restrictive Cardiomyopathy

open access: yes, 2016
Causes of a restrictive physiology and the differential diagnosis and therapy of restrictive cardiomyopathy are presented.
Jason McCourt, Randy Ray Richardson
core   +3 more sources

FAMILIAL RESTRICTIVE CARDIOMYOPATHY

Australian and New Zealand Journal of Medicine, 1988
Abstract:The cases of a father and daughter with idiopathic restrictive cardiomyopathy are described. In contrast to other forms of cardiomyopathy, this type is rarely familial.
Con Aroney   +2 more
exaly   +6 more sources

Restrictive Cardiomyopathy in Childhood

Heart Failure Clinics, 2010
Depending on the part of the world one lives in, restrictive cardiomyopathy is either one of the rarest forms of cardiomyopathy in childhood, with no cause usually identified, or it is secondary to a poorly understood disease, endomyocardial fibrosis, that is endemic in some populations.
Susan W Denfield, Steven A Webber
exaly   +3 more sources

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