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Genetics of Restrictive Cardiomyopathy
Heart Failure Clinics, 2010Restrictive physiology, a severe form of diastolic dysfunction, is characteristically observed in the setting of constrictive pericarditis and myocardial restriction. The latter is commonly due to systemic diseases, some of which are inherited as mendelian traits (eg, hereditary amyloidosis), while others are multifactorial (eg, sarcoidosis).
Petros Syrris
exaly +3 more sources
Genetic Insights into Primary Restrictive Cardiomyopathy
Journal of Clinical Medicine, 2022 Restrictive cardiomyopathy is a rare cardiac disease causing severe diastolic dysfunction, ventricular stiffness and dilated atria. In consequence, it induces heart failure often with preserved ejection fraction and is associated with a high mortality ...
Andreas Brodehl +2 more
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Hypertrophic Cardiomyopathy and Primary Restrictive Cardiomyopathy: Similarities, Differences and Phenocopies [PDF]
Journal of Clinical Medicine, 2021 Hypertrophic cardiomyopathy (HCM) and primary restrictive cardiomyopathy (RCM) have a similar genetic background as they are both caused mainly by variants in sarcomeric genes.
Riccardo Vio +2 more
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, 2018 Restrictive cardiomyopathy (RCM) is an uncommon myocardial disease, characterized by impaired filling of the ventricles in the presence of normal wall thickness and systolic function.
Aalap Chokshi, Amanda R. Vest
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Pacing and Clinical Electrophysiology, 2009
Background: Restrictive cardiomyopathy is characterized by ventricular diastolic dysfunction with a clinical course in childhood that is often progressive despite medical therapy. Methods: A review of the literature and clinical experience was used to summarize the natural history of this oftentimes devastating disease with ...
Steven, Zangwill, Robert, Hamilton
+7 more sources
Background: Restrictive cardiomyopathy is characterized by ventricular diastolic dysfunction with a clinical course in childhood that is often progressive despite medical therapy. Methods: A review of the literature and clinical experience was used to summarize the natural history of this oftentimes devastating disease with ...
Steven, Zangwill, Robert, Hamilton
+7 more sources
Current Treatment Options in Cardiovascular Medicine, 2000
Of the three major functional categories of cardiomyopathies (dilated, hypertrophic, and restrictive), the restrictive cardiomyopathies (RCMs) are the least common in the Western world, but unfortunately often are associated with the greatest morbidity and mortality. Infiltrative disease of the myocardium (often caused by amyloidosis) is a common cause
, Artz, , Wynne
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Of the three major functional categories of cardiomyopathies (dilated, hypertrophic, and restrictive), the restrictive cardiomyopathies (RCMs) are the least common in the Western world, but unfortunately often are associated with the greatest morbidity and mortality. Infiltrative disease of the myocardium (often caused by amyloidosis) is a common cause
, Artz, , Wynne
openaire +2 more sources
Current Opinion in Cardiology, 1994
Restrictive cardiomyopathy has always been a fairly common cause of cardiac death in the tropics through endomyocardial fibrosis. In temperate climates, amyloidosis is the most common form of the disease, whereas Löffler's endocarditis is quite rare. Amyloidosis is more frequently encountered as the population ages, but restrictive cardiomyopathy is ...
N, Spyrou, R, Foale
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Restrictive cardiomyopathy has always been a fairly common cause of cardiac death in the tropics through endomyocardial fibrosis. In temperate climates, amyloidosis is the most common form of the disease, whereas Löffler's endocarditis is quite rare. Amyloidosis is more frequently encountered as the population ages, but restrictive cardiomyopathy is ...
N, Spyrou, R, Foale
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The Restrictive Cardiomyopathies
Cardiology Clinics, 1988In parallel with the rapidly developing interest in the diastolic properties of ventricular function in the 1970s, the restrictive cardiomyopathies have taken their place as the third major category of primary heart muscle disease. The restrictive cardiomyopathies are characterized by primary abnormalities of diastolic ventricular function with normal ...
J S, Child, J K, Perloff
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, 2011 Restrictive cardiomyopathy is a condition characterized by normal left ventricular cavity size and systolic function but with increased myocardial stiffness [1]. This makes the ventricle incompliant and fi ll predominantly in early diastole.
Michael Y. Henein, Mary Sheppard
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Annual Review of Medicine, 1984
Restrictive cardiomyopathy is a descriptive clinical and hemodynamic syndrome emphasizing the pathophysiologic mechanisms by which myocardial hypertrophy and/or infiltrative processes cause cardiocirculatory morbidity. This diagnosis can be made with precision only after pericardial construction is excluded and myocardial biopsy has identified the ...
J R, Benotti, W, Grossman
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Restrictive cardiomyopathy is a descriptive clinical and hemodynamic syndrome emphasizing the pathophysiologic mechanisms by which myocardial hypertrophy and/or infiltrative processes cause cardiocirculatory morbidity. This diagnosis can be made with precision only after pericardial construction is excluded and myocardial biopsy has identified the ...
J R, Benotti, W, Grossman
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