A Novel Method of Human Adipose-Derived Stem Cell Isolation with Resultant Increased Cell Yield
, 2016 Ruth Tevlin +13 more
openalex +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Harvesting the Spin-Orbit Interaction of Light to Generate Helicity-Dependent Complex Rotational Motion in Optically Trapped Mesoscopic Matter. [PDF]
NanophotonicsKumar RN +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Biomechanical Comparison of 3 Suturing Techniques for Lateral Meniscus Radial Tears Using a 6 Degrees of Freedom Robotic Simulator. [PDF]
Orthop J Sports MedHosokawa H +9 more
europepmc +1 more source
Researchers’ choice of the number and range of levels in experiments affects the resultant variance-accounted-for effect size [PDF]
, 2016 Kensuke Okada, Takahiro Hoshino
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Calculation and analysis of passive earth pressure under ultimate stress conditions. [PDF]
Sci RepLiu G, Dang F, Wang X, Li Y, Zheng W.
europepmc +1 more source
Overdetermined Systems of Equations, Newton Polyhedra, and Resultants
, 2019 Leonid Monin
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source