Results 141 to 150 of about 78,960,767 (328)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Results, Results, Results

, 2019
Angela Daly, Julie Brown
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Assessing IRI vs. PI as a measurement of pavement smoothness : final report, June 2006.

R106-003A Pavement smoothness specification that allows either the International Roughness Index (IRI) or Profile Index (PI) to measure pavement smoothness would be advantageous to both industry and MoDOT.
Nemmers, Charles J., Gagarin, Nicolas, University of Missouri--Columbia, Mekemson, James R.   +3 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial.

Journal of the American Medical Association (JAMA), 2002
J. Rossouw, G. Anderson, Ross L. Prentice, Andrea Z. LaCroix, C. Kooperberg, Marcia L. Stefanick, R. Jackson, S. A. Beresford, Barbara V. Howard, Karen C. Johnson, J. Kotchen, Judith K. Ockene   +11 more
semanticscholar   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Errors in Results [PDF]

JAMA Internal Medicine, 2021
openaire   +2 more sources

Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey.

Journal of the American Medical Association (JAMA), 1998
D. Eisenberg, Roger B. Davis, S. Ettner, Sarit Appel, Sonja Wilkey, M. Rompay, Ronald C. Kessler   +6 more
semanticscholar   +1 more source