Results 71 to 80 of about 86,169 (304)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Reducing dependence of modeled resuspended volcanic ash on meteorological grid resolution
Remobilized volcanic ash from ground deposits can present significant hazards to human health, infrastructure, and aviation. Modeling of ash remobilization events is an important tool that can provide information on the timing and magnitude to assist in ...
Alice M. Crawford +3 more
doaj +1 more source
Review of resuspension models. [Particle resuspension]
Resuspension of particles is classified, according to the prominent path of exposure and the type of consideration involved in estimating concentrations, as general resuspension, local resuspension, and transfer resuspension.
Healy, J. W.
core
A yearlong campaign to examine sediment resuspension was conducted in large, shallow and eutrophic Lake Taihu, China, to investigate the influence of vegetation on sediment resuspension and its nutrient effects. The study was conducted at 6 sites located
Mengyuan Zhu (729869)
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Contribution of coastal seiches to sediment transport in a microtidal semi-enclosed bay
Moorings and axial surveys using acoustic Doppler current profilers in microtidal Masan Bay were conducted to reveal impacts of coastal seiches on sediment behaviors.
Jun Young Seo +5 more
doaj +1 more source
The intensity of sediment resuspension and sedimentation in the eastern part of the Bothnian Bay near the Hanhikivi cape, where the nuclear power plant ‘Hanhikivi-1’ will be constructed, has been assessed for the first time by means of ...
Stanislav D. Martyanov +3 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

