Results 161 to 170 of about 132,275 (287)
Multi-omics analysis identifies CCNB1 as a cell cycle factor driving glioblastoma progression and its inhibition by resveratrol. [PDF]
Liu B +6 more
europepmc +1 more source
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin +7 more
wiley +1 more source
Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases. [PDF]
Shen CY, Li CP, Yu JT, Ho YJ, Tsai RY.
europepmc +1 more source
Glycoprotein Ib activation by thrombin stimulates the energy metabolism in human platelets [PDF]
Corona de la Pena, Norma +4 more
core +3 more sources
Fruit bioactive compounds offer antioxidant, anti‐inflammatory, and preventive benefits, yet extraction is hindered by poor solubility and conventional methods using toxic solvents and high energy. This review evaluates traditional and advanced eco‐friendly technologies, highlighting efficiency, selectivity, and sustainability.
Abadi Gebreyesus Hndeya +2 more
wiley +1 more source
Curcumin Nanoformulations for Dermatological Applications: From Nutraceuticals to Nanocarriers
Nanotechnology‐based delivery platforms enhance the cutaneous administration of curcumin. Loading free curcumin into polymeric micelles, metal‐based nanoparticles, nanogels/hydrogels, liposomes, polymeric nanoparticles, or nanoemulsions/nanocrystals helps address its low solubility, poor stability and limited skin permeation. As a result, these systems
Stephany Celeste Gutiérrez‐Ruiz +13 more
wiley +1 more source
Repurposing Hetrombopag for Multiple Myeloma by Targeting PNPO: A Celastrol‐Inspired Approach
Hetrombopag targeted PNPO to inhibit multiple myeloma. ABSTRACT Multiple myeloma (MM) is a malignancy of plasma cells whose excessive immunoglobulin production elevates reactive oxygen species (ROS), promoting pathogenesis. Active compounds from Traditional Chinese Medicine, such as celastrol, can exert antitumour effects by further increasing ROS ...
Tianyi Yu +9 more
wiley +1 more source
Targeting cancer hallmarks using resveratrol: isolation, formulation, and mechanisms of action. [PDF]
Talib WH +9 more
europepmc +1 more source
Chimeric antigen receptor (CAR) T‐cell therapy, although revolutionary for haematological malignancies, faces significant challenges, including T‐cell exhaustion, limited persistence, and treatment‐related toxicity. The integration of small‐molecule compounds offers a promising strategy to overcome these limitations.
Rangzi Yi +3 more
wiley +1 more source

