Results 201 to 210 of about 92,194 (291)

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Resveratrol modulates pancreatic proteotoxic stress and metabolic dysfunction in human IAPP transgenic mice. [PDF]

Front Endocrinol (Lausanne)
Iglesias-Fortes S, García-Aguilar A, García G, Rodríguez-Cueto C, Fernández-Ruiz J, Martín-Cámara O, Menéndez JC, Benito M, Guillén C.   +8 more
europepmc   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Network Pharmacology-Guided Phytochemical Polypharmacology: Integrating Molecular Mechanisms, Experimental Validation and Clinical Translation. [PDF]

Int J Mol Sci
Singh SA, Wankhade P, Godvarthi R, Warbhe R, Khartade P, Basheeruddin M, Narwade S.   +6 more
europepmc   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

Combined Vitamin D and Resveratrol Treatment Attenuates Motor Deficits and Neurodegeneration in a 6-OHDA Mouse Model of Parkinson's Disease in Male Mice: A Focus on Sirt1 and Lingo-1 Pathways in the Ventral Tegmental Area. [PDF]

Brain Behav
Soti M, Ilaghi M, Kohlmeier KA, Shahabinejad E, Pirmoradi Z, Shabani M.   +5 more
europepmc   +1 more source

From Food Waste to Phytochemicals: Green Recovery, Food‐Matrix Applications, and Metabolic‐Health Translation of Residue‐Derived Polyphenols

Phytochemicals in Food and Medicine, Volume 1, Issue 4, December 2026.
Decision rule: The lowest‐scoring gate determines overall readiness. Suggested concise take‐home message: Residue‐derived polyphenols should advance from chemically defined sources through food‐grade recovery and real‐matrix validation to realistic exposure‐based health evidence.
Chandan Kumar Sahu, Syed Irshaan, S. Karthikeyan   +2 more
wiley   +1 more source

The Role of SIRT1 in Mediating Bone Marrow Edema and Its Interface With Bone Remodeling. [PDF]

Immun Inflamm Dis
Chen Y, Li X, Zheng Z, Liu Z, Xu T, Tang Y.   +5 more
europepmc   +1 more source

Chios Mastic in Well‐Controlled Hypertension: Findings From the HYPER‐MASTIC Randomized Controlled Trial

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Residual cardiovascular risk persists in patients with adequately controlled hypertension, driven partly by inflammation, oxidative stress and endothelial dysfunction. Chios mastic (Pistacia lentiscus var. Chia) has shown antihypertensive, antioxidant and vascular effects in experimental and clinical settings.
Ioanna Panagiota Kalafati, Anastasia‐Areti Kyriazopoulou‐Korovesi, Evangelia Mentsiou‐Nikolaou, Maria Papaioannou, Christina Konstantaki, Lasthenis Angelidakis, Despoina D. Gianniou, Eleni V. Mikropoulou, Panagiota Giardoglou, Dimitrios Valakos, Giannis Vatsellas, HYPER‐MASTIC Consortium, Ioanna Andreadou, Efstathios Manios, Maria Halabalaki, Ioannis P. Trougakos, George V. Dedoussis, Kimon Stamatelopoulos   +17 more
wiley   +1 more source