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Chemopreventive effects of resveratrol and resveratrol derivatives
Annals of the New York Academy of Sciences, 2011Resveratrol is considered to have a number of beneficial effects. Recently, our group modified the molecule and synthesized a number of compounds with different biochemical effects. Polymethoxy and polyhydroxy derivatives of resveratrol were shown to inhibit tumor cell growth in various cell lines and inflammation pathways (cyclooxygenases activity ...
Szekeres, Thomas +4 more
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Resveratrol and Resveratrol Analogues—Structure—Activity Relationship
Pharmaceutical Research, 2010Resveratrol (3,4',5-trihydroxy-trans-stilbene) is a compound found in wine and is held responsible for a number of beneficial effects of red wine. Besides the prevention of heart disease and significant anti-inflammatory effects, resveratrol might inhibit tumor cell growth and even play a role in the aging process.
Szekeres, Thomas +3 more
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Critical Reviews in Food Science and Nutrition, 2013
Peanuts are important dietary food source of resveratrol with potent antioxidant properties implicated in reducing risk of cancer, cardiovascular and Alzheimer's disease, and delaying aging. Resveratrol is a naturally occurring stilbene phytoalexin phenolic compound produced in response to a variety of biotic and abiotic stresses.
Jocelyn M, Sales, Anna V A, Resurreccion
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Peanuts are important dietary food source of resveratrol with potent antioxidant properties implicated in reducing risk of cancer, cardiovascular and Alzheimer's disease, and delaying aging. Resveratrol is a naturally occurring stilbene phytoalexin phenolic compound produced in response to a variety of biotic and abiotic stresses.
Jocelyn M, Sales, Anna V A, Resurreccion
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Resveratrol and chemoprevention
Cancer Letters, 2009Resveratrol is a phytoalexin, highly abundant in skins of red grapes and moderately abundant in peanuts and blueberries. Originally a constituent of oriental medicines, it has lately been rediscovered for a plethora of beneficial properties such as anti-cancer, anti-aging, antiviral, cardiovascular and neuroprotective effects, thereby making it one of ...
Shyamal K, Goswami, Dipak K, Das
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American Journal of Lifestyle Medicine, 2012
Resveratrol is a polyphenolic compound found in many products commonly consumed in the American diet. The reported benefits of resveratrol are broad and include antiaging effects, antioxidant effects, anticancer effects, neuroprotective effects, and an array of cardiovascular benefits such as improved cholesterol profiles, reduced atherosclerosis ...
Nicole D. Gillespie, Thomas L. Lenz
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Resveratrol is a polyphenolic compound found in many products commonly consumed in the American diet. The reported benefits of resveratrol are broad and include antiaging effects, antioxidant effects, anticancer effects, neuroprotective effects, and an array of cardiovascular benefits such as improved cholesterol profiles, reduced atherosclerosis ...
Nicole D. Gillespie, Thomas L. Lenz
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Antioxidants & Redox Signaling, 2008
Resveratrol, a red wine and grape-derived phytoalexin, possesses diverse biochemical and physiological functions that are relevant to human health and disease. The emergent properties of resveratrol have forced us to rethink the biomedical significance of the wine culture.
BERTELLI, ALBERTO +5 more
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Resveratrol, a red wine and grape-derived phytoalexin, possesses diverse biochemical and physiological functions that are relevant to human health and disease. The emergent properties of resveratrol have forced us to rethink the biomedical significance of the wine culture.
BERTELLI, ALBERTO +5 more
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Resveratrol Is Absorbed in the Small Intestine as Resveratrol Glucuronide
Biochemical and Biophysical Research Communications, 2000We have studied the absorption and metabolism of resveratrol in the jejunum in an isolated rat small intestine model. Only small amounts of resveratrol were absorbed across the enterocytes of the jejunum and ileum unmetabolised. The major compound detected on the serosal side was the glucuronide conjugate of resveratrol (96.5% +/- 4.6 of the amount ...
Kuhnle, G +7 more
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2001
Since the discovery of trans-resveratrol (3,5,4’-trihydroxystilbene) as a constituent of wine by Siemann and Creasy, first reported in 1992 (1), the possibility that this compound, almost unique to red wine among constituents of the human diet, may in large measure account for the putative health benefits of this beverage beyond its mere content of ...
G J, Soleas +2 more
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Since the discovery of trans-resveratrol (3,5,4’-trihydroxystilbene) as a constituent of wine by Siemann and Creasy, first reported in 1992 (1), the possibility that this compound, almost unique to red wine among constituents of the human diet, may in large measure account for the putative health benefits of this beverage beyond its mere content of ...
G J, Soleas +2 more
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Resveratrol: A Polyphenol for All Seasons
2005The history of resveratrol, the active ingredient in red grapes, peanuts, berries, and several other food plants, indirectly dates back to the Ayurveda, the ancient Indian treatise on the science of longevity. Although once considered a disadvantage, resveratrol’s ability to modulate multiple cellular targets makes it suitable for the prevention and ...
Bharat Aggarwal, Shishir Shishodia
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Commentary on Resveratrol and Hormesis: Resveratrol—a hormetic marvel in waiting?
Human & Experimental Toxicology, 2010Hormesis is a phenomenon in which adaptive responses to low doses of otherwise-harmful factors (also called mild stressors) make cells and organisms more robust. In their review, Calabrese et al. provide evidence for resveratrol acting hormetically in different types of human cell lines.
Francine Z, Marques, Brian J, Morris
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