Results 71 to 80 of about 92,194 (291)

Estrogen and Resveratrol Regulate Rac and Cdc42 Signaling to the Actin Cytoskeleton of Metastatic Breast Cancer Cells

open access: yesNeoplasia: An International Journal for Oncology Research, 2007
Estrogen and structurally related molecules play critical roles in breast cancer. We reported that resveratrol (50 µM), an estrogen-like phytosterol from grapes, acts in an antiestrogenic manner in breast cancer cells to reduce cell migration and to ...
Nicolas G. Azios   +5 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Prostate cancer targeting using replication-selective adenoviruses in combination with phytochemicals [PDF]

open access: yes, 2009
PhD 2009 QMOncolytic adenoviral mutants have demonstrated good safety profiles but, despite some encouraging clinical results, efficacy as a single agent was limited. Combinations with conventional chemo- or radiotherapy significantly enhanced the anti-
Adam, Virginie Sarah
core   +3 more sources

Resveratrol Attenuates High-Fat Diet-Induced Disruption of the Blood-Brain Barrier and Protects Brain Neurons from Apoptotic Insults

open access: yes, 2017
The blood-brain barrier (BBB) maintains brain microenvironment. Our previous study showed that oxidized low-density lipoprotein (oxLDL) can damage the BBB by inducing apoptosis of cerebrovascular endothelial cells.
Chang, Huai-Chia;Tai, Yu-Ting;Cherng, Yih-Giun;Lin, Jia-Wei;Liu, Shing-Hwa;Chen, Ta-Liang;Chen, Ruei-Ming   +1 more
core   +1 more source

Resveratrol inhibits extracellular matrix degradation in cytokine-challenged TMJ cartilage

open access: yes, 2020
Lu, X. LucasTemporomandibular joint disease (TMD) includes a group of conditions that lead to pain and joint impairment. The prevalence of Temporomandibular joint disorder is higher among the younger population affecting about 11 million Americans ...
Paul, Sushmita Bidyut
core   +1 more source

Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies [PDF]

open access: yes, 2013
Overweight and obesity are major problems of public health in many countries worldwide. Overweight can cause severe diseases such as type II diabetes mellitus, hypertension, stroke, heart failure and several types of cancer.
Hirzel, Estelle
core   +1 more source

Nutrition and Metabolic Diseases: A Systematic Review of Functional Foods, Medicinal Plants, Phytochemicals, Bioactive Compounds and Nutrients Effective Against Metabolic Diseases

open access: yesFood Chemistry International, EarlyView.
The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi   +2 more
wiley   +1 more source

Resveratrol inhibited colorectal cancer progression by reducing oxidative DNA damage by targeting the JNK signaling pathway

open access: yesHeliyon
Recent evidence has proved that resveratrol as a natural polyphenol has great anti-cancer and anti-proliferative effects in cancer cells. In this study, we aimed to examine the protective effects of resveratrol in rats with 1,2-dimethylhydrazine (DMH ...
Masoumeh Maleki   +4 more
doaj   +1 more source

The cognitive and cerebral blood flow effects of the polyphenol resveratrol in healthy, young humans [PDF]

open access: yes
The polyphenol trans-resveratrol interacts with a number of mechanisms relevant to brain function and has demonstrated preserved and enhanced cognitive function in animal models as a result.
Wightman, Emma
core  

Resveratrol Promotes Osteogenesis of Human Mesenchymal Stem Cells by Upregulating Runx2 Gene Expression Via the Sirt1/Foxo3a Axis

open access: yes, 2012
Reports of the bone-protective effects of resveratrol, a naturally occurring phytoestrogen and agonist for the longevity gene SIRT1, have highlighted this compound as a candidate for therapy of osteoporosis.
Tseng, Pei-Chi; Hou, Sheng-Mou; Chen, Ruey-Jien; Peng, Hsiao-Wen; Hsieh, Chi-Fen; Kuo, Min-Liang; Yen, Men-Luh   +1 more
core   +1 more source

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