Results 131 to 140 of about 53,193 (289)

Pralsetinib: A Drug Review

Indian Journal of Medical and Paediatric Oncology
REarranged during Transfection (RET) is a transforming proto-oncogene that codes for the tyrosine kinase receptor. Pralsetinib is an orally bioavailable, selective inhibitor of mutant forms and fusions involving the RET proto-oncogene.
Abha Deshpande, Ryan Varghese, Jainam Karsiya, Praveen Jha, Padmaj Kulkarni   +4 more
doaj   +1 more source

Selpercatinib monotherapy in a Chinese patient with RET fusion/EGFR co-mutated nonsmall cell lung cancer from the Phase II LIBRETTO-321 study: a case report

, 2023
Lin Wu, Ying Cheng, Dingzhi Huang, Yuping Sun, Chengzhi Zhou, Jianying Zhou, Ye Guo, Jingxin Shao, Wanli Zhang, Shun Lü   +9 more
openalex   +1 more source

Durable Response to Combined Osimertinib and Pralsetinib Treatment for Osimertinib Resistance Due to Novel IntergenicANK3-RETFusion inEGFR-Mutated Non–Small-Cell Lung Cancer [PDF]

, 2022
Edyta Maria Urbanska, Jens Benn Sørensen, Linea Cecilie Melchior, Junia C. Costa, Eric Santoni‐Rugiu   +4 more
openalex   +1 more source

Ossification of the cranium of Inpaichthys kerri (Characiformes: Acestrorhamphidae) with discussion of paedomorphic traits in the genus

Journal of Anatomy, EarlyView.
In this study, we present a detailed description of the cranial development of Inpaichthys kerri (Characiformes: Acestrorhamphidae), highlighting important topics such as pedomorphic characters and their relationship with ontogeny and phylogeny, as well as ossification sequences unique to the species. Abstract The study of development provides valuable
Yasmim De Santana Santos, Manoela M. F. Marinho   +1 more
wiley   +1 more source

A phase 1 study of oral LOXO 292 in adult patients with advanced solid tumors, including RET-fusion non-small cell lung cancer, medullary thyroid cancer and other tumors with increased RET activity [PDF]

, 2017
Alexander Drilon, Todd M. Bauer, Vivek Subbiah, Maria E. Cabanillas, N. Lahkani, Lori J. Wirth, Geoffrey R. Oxnard, Skyler Smith, Todd Eary, Scott Cruickshank, Mai Nguyen, S. Michael Rothenberg   +11 more
openalex   +1 more source

Exceptional Responses to Selpercatinib in RET Fusion–Driven Metastatic Pancreatic Cancer [PDF]

, 2023
Deepak Bhamidipati, Sireesha Yedururi, Jason T. Huse, Sri Veda Chinapuvvula, Jie Wu, Vivek Subbiah   +5 more
openalex   +1 more source

Genetically modified natural killer cells specifically recognizing the tumor-associated antigens ErbB2/HER2 and EpCAM [PDF]

, 2007
The continuously growing natural killer (NK) cell line NK-92 is highly cytotoxic against malignant cells of various origin without affecting normal human cells.
Klingemann, Hans-Georg, Müller, Tina, Tonn, Torsten, Uherek, Barbara, Uherek, Christoph, Wels, Winfried S.   +5 more
core  

Comparative endocranial anatomy in the crocodylians Leidyosuchus canadensis and Stangerochampsa mccabei from the upper Cretaceous of Alberta, Canada

Journal of Anatomy, EarlyView.
Leidyosuchus canadensis and Stangerochampsa mccabei share endocranial features such as posterior projection of a neurovascular canal in the maxilla and a paratympanic sinus system most similar to those of small‐bodied and young extant crocodylians, suggesting that these pedomorphic features may reflect the ancestral crocodylian condition.
G. Donzé, G. Perrichon, P. Vincent, F. Therrien, J. E. Martin   +4 more
wiley   +1 more source

Institutional Investor Attention

The Journal of Finance, EarlyView.
ABSTRACT Using data on Internet news reading, we measure fund‐level attention to both aggregate and firm‐specific news and relate it to fund portfolio allocation decisions. In the time series, we find that funds shift attention toward macroeconomic news during periods of high aggregate volatility.
ALAN KWAN, YUKUN LIU, BEN MATTHIES
wiley   +1 more source

Emotion Recognition from Acted and Spontaneous Speech [PDF]

, 2014
Dizertační práce se zabývá rozpoznáním emočního stavu mluvčích z řečového signálu. Práce je rozdělena do dvou hlavních častí, první část popisuju navržené metody pro rozpoznání emočního stavu z hraných databází.
Atassi, Hicham
core