ABSTRACT Cabozantinib is a small‐molecule tyrosine kinase inhibitor approved for the treatment of various locally advanced or metastatic solid tumors. The phase 1b COSMIC‐021 study evaluated cabozantinib as a monotherapy or in combination with atezolizumab in patients with advanced solid tumors, including castration‐resistant prostate cancer (CRPC ...
Jason H. Williams +2 more
wiley +1 more source
Synergistic role of molecular imaging and genomics in thyroid cancer management: from diagnosis to personalized treatment. [PDF]
Ahmadi S +5 more
europepmc +1 more source
Abstract Although small intestinal neuroendocrine tumours (SI‐NET) Grade 1 (G1) and 2 (G2) are often studied together, clinical course and response to treatment may differ. We hypothesized that these tumour groups express different markers in blood that may inform future treatment strategies. Blood from 107 SI‐NET patients (G1 n = 64, G2 n = 43) and 50
Malin Grönberg +2 more
wiley +1 more source
How to manage radioiodine-refractory thyroid cancer in the era of precision medicine. [PDF]
Karapanou O +3 more
europepmc +1 more source
Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde +2 more
wiley +1 more source
Acquired TPM3::NTRK1 fusion as a novel off-target resistance mechanism to selpercatinib in RET-positive lung adenocarcinoma: a case report. [PDF]
Choudhury R +6 more
europepmc +1 more source
Radioiodine-Refractory Differentiated Thyroid Cancer: Definition, Molecular Mechanisms, and Advances in Precision Therapy. [PDF]
Li Y, He Z.
europepmc +1 more source
Modern therapeutic approaches in cholangiocarcinoma: A narrative review of key biomarkers and clinical trials. [PDF]
Almeida A +10 more
europepmc +1 more source
Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review). [PDF]
Wang J, Liu Z, Zhang Q, Sun W.
europepmc +1 more source
Management of thyroid disorders: from autoimmunity to malignancy - novel insights from precision medicine: <i>How to manage thyroid diseases: from autoimmunity to malignancy</i> Special Issue. [PDF]
Saltiki K, Effraimidis G.
europepmc +1 more source

