Results 21 to 30 of about 47,239 (175)

Patient induced pluripotent stem cells identify specificities of a reticular pseudodrusen phenotype in age-related macular degeneration [PDF]

Genome Medicine
Background Age-related macular degeneration (AMD) is a leading cause of vision loss. Reticular pseudodrusen (RPD), deposits on the apical side of the retinal pigment epithelium (RPE), signify a distinctive and critical AMD phenotype. Yet, their molecular
Jenna C. Hall, Kavitha Krishna Sudhakar, Maciej Daniszewski, Anne Senabouth, Carla J. Abbott, Helena H. Liang, Himeesh Kumar, Grace E. Lidgerwood, Mehdi Mirzaei, Jessica YW Ma, Trevor Atkeson, Yumiko Hirokawa, Emeline F. Nandrot, Alexander Barnett, Chantal Cazevieille, Gaël Manes, Simon Mountford, Philip Thompson, Erica L. Fletcher, Zhichao Wu, Melanie Bahlo, Brendan R. E. Ansell, Daniel Paull, Alex W. Hewitt, Robyn H. Guymer, Joseph E. Powell, Alice Pébay   +26 more
doaj   +3 more sources

Correlation of Histologic Features with In Vivo Imaging of Reticular Pseudodrusen [PDF]

Ophthalmology, 2016
To determine the histologic and cellular correlates in the retina and retinal pigment epithelium (RPE) with the presence of optical coherence tomography-defined reticular pseudodrusen (RPD).Observation case using immunocytochemistry of an exenterated eye with immediate fixation after removal.Two patients, one with confirmed RPD and the other with mid ...
Ursula Greferath, Robyn H Guymer, Kirstan A Vessey   +2 more
exaly   +8 more sources

Reticular Pseudodrusen Are Associated With More Advanced Para-Central Photoreceptor Degeneration in Intermediate Age-Related Macular Degeneration [PDF]

Invest Ophthalmol Vis Sci, 2022
Purpose The purpose of this study was to examine retinal topographical differences between intermediate age-related macular degeneration (iAMD) with reticular pseudodrusen (RPD) versus iAMD without RPD, using high-density optical coherence tomography ...
Matt Trinh, Natalie Eshow, D. Alonso-Caneiro, M. Kalloniatis, L. Nivison-Smith   +4 more
semanticscholar   +3 more sources

Electrophysiological function in eyes with reticular pseudodrusen according to fundus distribution. [PDF]

PLoS ONE, 2018
Reticular pseudodrusen (RPD) could be present not only in the posterior pole but extramacular area also as a confluent morphological pattern. Thus RPD can be classified by the fundus distribution for the assessment of visual prognosis.
Mingui Kong, Jaemoon Yoon, Don-Il Ham
doaj   +3 more sources

Choroidal Changes Associated with Reticular Pseudodrusen

Investigative Opthalmology & Visual Science, 2012
To analyze choroidal changes associated with reticular pseudodrusen by indocyanine green angiography (ICGA) and enhanced depth imaging spectral-domain optical coherence tomography (EDI SD-OCT).Twenty-two consecutive patients (22 eyes) with reticular pseudodrusen, and without medium/large drusen, underwent ICGA and EDI OCT.
QUERQUES , GIUSEPPE, Querques L, Forte R, Coscas F, Massamba N, Souied EH   +5 more
core   +7 more sources

Decreased Macular Choriocapillaris Perfusion in Eyes With Macular Reticular Pseudodrusen Imaged With Swept-Source OCT Angiography [PDF]

Invest Ophthalmol Vis Sci, 2023
Purpose To determine if macular reticular pseudodrusen (RPD) were associated with markers of impaired macular choroidal perfusion, we investigated measurements of macular choriocapillaris (CC) flow deficits (FDs), CC thickness, and mean choroidal ...
Jianqing Li, Ziyu Liu, Jie Lu, Mengxi Shen, Yuxuan Cheng, Nadia Siddiqui, Hao Zhou, Qinqin Zhang, Jeremy Liu, Gissel Herrera, Farhan E. Hiya, Giovanni Gregori, Ruikang K. Wang, P. Rosenfeld   +13 more
semanticscholar   +2 more sources

A Deep Learning Framework for the Detection and Quantification of Reticular Pseudodrusen and Drusen on Optical Coherence Tomography [PDF]

Transl Vis Sci Technol, 2022
Purpose The purpose of this study was to develop and validate a deep learning (DL) framework for the detection and quantification of reticular pseudodrusen (RPD) and drusen on optical coherence tomography (OCT) scans. Methods A DL framework was developed
R. Schwartz, Hagar Khalid, S. Liakopoulos, Y. Ouyang, Coen de Vente, C. González-Gonzalo, Aaron Y. Lee, R. Guymer, E. Chew, C. Egan, Zhichao Wu, Himeesh Kumar, Joseph Farrington, C. S'anchez, A. Tufail   +14 more
semanticscholar   +2 more sources

Age-related macular degeneration eyes presenting with cuticular drusen and reticular pseudodrusen [PDF]

Scientific Reports, 2022
This study aimed to describe the clinical characteristics of age-related macular degeneration (AMD) eyes with both cuticular drusen (CD) and reticular pseudodrusen (RPD).
Je Moon Yoon, Dong Hoon Shin, Mingui Kong, Don-Il Ham   +3 more
doaj   +2 more sources

Spatial Analysis Reveals Vascular Changes in Retinal and Choroidal Vessel Perfusion in Intermediate AMD With Reticular Pseudodrusen [PDF]

Invest Ophthalmol Vis Sci
Purpose To examine the effect of reticular pseudodrusen (RPD) on retinal and choroidal vessel perfusion (VP) topography in intermediate age-related macular degeneration (iAMD) using refined spatial analyses.
Judy Nam, L. Nivison-Smith, Matt Trinh
semanticscholar   +2 more sources

ASSESSING RELIABILITY AND AGREEMENT IN TOPOGRAPHIC MEASUREMENT OF RETICULAR PSEUDODRUSEN AREA [PDF]

Retina
Supplemental Digital Content is Available in the Text. Combined near-infrared reflectance and optical coherence tomography seems the most reliable imaging approach to assess topographic distribution and area of reticular pseudodrusen, a potential ...
Mariano Cozzi, A. Trinco, Francesco Romano, Sandrine A. Zweifel, G. Staurenghi, A. Invernizzi   +5 more
semanticscholar   +2 more sources