Results 141 to 150 of about 93,775 (268)

A glycoprotein VI signaling defect in newly formed platelets generated in stress thrombopoiesis

open access: yes
BACKGROUND: Newly produced platelets are thought to be more functional than their older counterparts. However, recent work suggests that murine platelets formed following immune-mediated thrombocytopenia possess a transient glycoprotein (GP) VI signaling
Sutherland, KD   +11 more
core   +1 more source

Expert Consensus on the Management of Hyperpigmentation Disorders in India: A Modified Delphi Study by the Pigmentary Disorders Society

open access: yesInternational Journal of Dermatology, EarlyView.
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar   +12 more
wiley   +1 more source

All platelets are not equal: COAT platelets

open access: yes, 2004
Collagen- and thrombin-activated (COAT) platelets were first described in 2000 and have attracted considerable interest, changing the interpretation of the way in which platelets contribute to thrombin generation and how their procoagulant activity is ...
Alberio, LJ, Clemetson, KJ
core  

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra   +5 more
wiley   +1 more source

Distinct Microbial and Host Proteome Signatures Relate to Proteolytic Activity in Gingival Crevicular Fluid in an Exploratory Study of Patients With Periodontitis

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Aim Risk assessment tools for periodontitis lack sufficient precision to predict disease progression. The aim of this exploratory study was to evaluate proteolytic activity (PA) in gingival crevicular fluid in relation to clinically assessed progression risk, microbial community composition and host proteome. Materials and Methods Samples were
Miguel Carda‐Diéguez   +10 more
wiley   +1 more source

Male genital lichen sclerosus

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas   +3 more
wiley   +1 more source

The Role of Oxidative Stress in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon   +3 more
wiley   +1 more source

Clinical significance of measuring reticulated platelets in infectious diseases. [PDF]

open access: yesMedicine (Baltimore), 2017
Liu QH, Song MY, Yang BX, Xia RX.
europepmc   +1 more source

Soft Tissue Substitutes: Current Biomaterials and Indications at Teeth and Implant Sites

open access: yesJournal of Periodontal Research, EarlyView.
This manuscript provides an updated overview of the current evidence on soft tissue graft substitutes for teeth and dental implants. When appropriately indicated, these biomaterials offer a reliable, less invasive alternative to autogenous grafts, effectively improving root coverage, keratinized mucosa width, and soft tissue thickness with reduced ...
Lorenzo Tavelli   +4 more
wiley   +1 more source

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