Results 191 to 200 of about 93,775 (268)

Sex‐Specific Proteomic Profiling Identifies Pregnancy Zone Protein as a Complement‐Linked Marker of Adverse Prognosis in Esophageal Adenocarcinoma

International Journal of Cancer, Volume 159, Issue 10, Page 2595-2605, 15 November 2026.
ABSTRACT Esophageal adenocarcinoma (EAC) exhibits marked male predominance with male‐to‐female ratios reaching 8.5:1, yet the molecular basis underlying this sex disparity remains poorly characterized. We analyzed 92 EAC specimens using mass spectrometry–based proteomics, comprising 47 female and 45 male tumors from treatment‐naïve patients ...
Alexander Quaas, Hanna Schiemann, Su Ir Lyu, Thomas Zander, Axel Hillmer, Hans Schlößer, Christiane J. Bruns, Reinhard Büttner, Bastian Grothey   +8 more
wiley   +1 more source

Isolation and phylogenetic characterization of <i>Sarcocystis singaporensis</i> isolates from Surabaya python snakes (<i>Malayopython reticulatus</i>) as a biological control agent for rats. [PDF]

Open Vet J
Eduardus Bimo A, Sunarso A, Yunus M, Suwanti LT, Mufasirin, Sediyoadi L, Putra AS, Rosalia NT, Dzahabiyyah N.   +8 more
europepmc   +1 more source

Regulation of IL‐13 Signaling by Retinoic Acid in Airway Epithelial Cells

The FASEB Journal, Volume 40, Issue 21, 15 November 2026.
Our proteomics and subsequent biochemical analyses reveal the effects of retinoic acid receptor (RAR) agonists, ATRA (pan‐RAR agonist), or CD1530 (RARγ agonist) in counteracting molecular changes induced by IL‐13 relevant to airway inflammation and remodeling, such as proteins involved in epithelial‐to‐mesenchymal transition (EMT) and extracellular ...
Vanshika Patel, Jianshi Yu, Mehari Weldemariam, Paul Shapiro, Deepak A. Deshpande, Maureen A. Kane   +5 more
wiley   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, Volume 13, Issue 61, 3 November 2026.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Platelet effector functions in inflammation. [PDF]

Res Pract Thromb Haemost
Escaig R, Kreutz L, Kaiser R, Nicolai L.
europepmc   +1 more source

Further Insights Into the Mechanisms of Lymph Node Metastasis

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Metastasis of malignant tumors arising from epithelial organs to sentinel lymph nodes has important implications for prognosis, staging, and therapeutic decision‐making. Recent insights into anatomic pathways, pathogenesis, molecular interactions, and genetic factors have encouraged scientists and clinicians to develop drugs that target ...
S. David Nathanson, Meghan J. O'Melia, Kelly C. Rosso, Ian S. Wood, Drishti Lall, Jenny T. Bui   +5 more
wiley   +1 more source

Altered thrombopoiesis in spontaneously hypertensive rats. [PDF]

Sci Rep
Rojo I, Millán-Aldaco D, Rincón-Heredia R, Martínez-Vieyra I, Rosales-García V, Aztatzi-Aguilar G, Pérez-Hernández N, Hernández-Cruz A, Cerecedo D.   +8 more
europepmc   +1 more source

Serpin A1 Cargo Within Tumour‐Derived Extracellular Vesicles Supports Pro‐Tumoural Bias of Neutrophils in Cancer

Journal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
ABSTRACT Tumour‐derived extracellular vesicles (EVs) or exosomes are critical mediators of the cancer‐immune system crosstalk, yet the mechanisms by which they reprogram neutrophil function in vivo remain insufficiently characterised. Here, we identify the serine protease inhibitor Serpin A1 as a predominant cargo component of small EVs (sEVs) released
Maksim Domnich, Ekaterina Pylaeva, Elena Siakaeva, Nastassia Kabankova, Agnieszka Bedzinska, Damian Sojka, Aneta Zebrowska, Marta Gawin, Maren Soldierer, Yaping Yu, Malwina Rist, Daniel Fochtman, Bernd Giebel, Iris Helfrich, Ilona Thiel, Basant Kumar Thakur, Cornelius H. L. Kürten, Helmut Hanenberg, Sonja Ludwig, Piotr Widlak, Stephan Lang, Monika Pietrowska, Jadwiga Jablonska   +22 more
wiley   +1 more source

Helicobacter pylori Infection Remodels Neutrophil‐Derived Extracellular Vesicles, Promoting Stress and Apoptosis in Infected Epithelial Cells

Journal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
We report that Helicobacter pylori reprograms neutrophils to release extracellular vesicles (HPN‐EVs) with distinct biophysical and molecular features. These neutrophil‐derived vesicles, enriched in neutrophil granule proteins, LL‐37 and pro‐apoptotic miRNAs, suppress epithelial PI3K/Akt signalling, increase ROS, and induce mitochondrial dysfunction ...
Anand Kumar Keshri, Suraj Singh Rawat, Durganand Thakur, Swati Sharma, Parul Mehra, Anubha Chaudhary, Ananaya Kapoor, Amit Prasad   +7 more
wiley   +1 more source

Platelets induce VISTA expression and modulate the ovarian tumor microenvironment. [PDF]

Platelets
Lee H, Sager B, Sood A, Afshar-Kharghan V, Cho MS.   +4 more
europepmc   +1 more source