Results 171 to 180 of about 573,457 (326)

Comparison of the Response to the CXCR4 Antagonist AMD3100 During Development of Retinal Organoids Derived from ES Cells and of Zebrafish Retina

, 2021
Yihui Wu, Jin Qiu, Shuilian Chen, Xi Chen, Jing Zhang, Jiejie Zhuang, Sian Liu, Meng Yang, Pan Zhou, Haoting Chen, Jian Ge, Keming Yu, Jing Zhuang   +12 more
openalex   +1 more source

OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis

Advanced Science, EarlyView.
OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu, An Shao, Bingtao Guan, Ziyao Luo, Weiyi Lai, Xiaoling Huang, Jun Liu, Jie Yan, Huimin Li, Xiangji Pan, Jiawei Wang, Zichang Su, Yih Chung Tham, Jie Yang, Haotian Lin, Juan Ye, Hongxia Xu, Jian Wu   +17 more
wiley   +1 more source

Efficacy and Safety of Intravitreal Brolucizumab in Chronic Central Serous Chorioretinopathy: A Retrospective Cohort Study

Clinical Ophthalmology
Somnath Chakraborty,1 Jay U Sheth,2 Santanu Ganguly,1 Rahul Reddy1 1Department of Retina Services, Retina Institute of Bengal, Siliguri, India; 2Department of Retina Services, Shantilal Shanghvi Eye Institute, Mumbai, IndiaCorrespondence: Somnath ...
Chakraborty S, Sheth JU, Ganguly S, Reddy R   +3 more
doaj  

Endothelial Cell‐Specific Molecule‐1 (ESM1): An Endogenous Anticoagulant and Protective Factor in Venous Thrombosis

Advanced Science, EarlyView.
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen, Xiaojuan Ge, Dongxu Fu, Haijun Mei, Feng Lv, Chao Yang, Jiahao Lu, Xiaozhong Shen, Bowen Li, Xiaoning Wang, Dong Liu   +10 more
wiley   +1 more source

Retina [PDF]

, 2020
openaire   +3 more sources

Photothermal Transport for Guiding Nanoparticles Through the Vitreous Humor

Advanced Science, EarlyView.
Nanosecond laser irradiation of the clinically approved dye indocyanine green (ICG) enables light‐guided nanoparticle transport within the vitreous humor. The combined use of ICG and pulsed laser illumination induces localized convection and thermophoresis, directing particles toward illuminated regions.
Léa Guerassimoff, Yera Ussembayev, Louise De Clerck, Deep Punj, Martijn van den Broek, Filip Beunis, Katrien Remaut, Kevin Braeckmans, Stefaan C. De Smedt, Félix Sauvage   +9 more
wiley   +1 more source

Endothelial stem cells of the retinal vasculature reside in the optic nerve. [PDF]

Nat Commun
Sakimoto S, Takigawa T, Oguchi A, Yoshihara M, Sekito S, Ueda C, Shiraki A, Shiki K, Yamaguchi K, Fukushima Y, Kitajima S, Murakawa Y, Quantock AJ, Nishida K.   +13 more
europepmc   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Large Language Models Triage of Retina Patient Emergency Telephone Calls: A Pilot Study. [PDF]

J Vitreoretin Dis
Chahal R, Beca F, Chau VQ, Kiryakoza L, Abousy M, Fan KC, Wykoff CC, Al-Khersan H.   +7 more
europepmc   +1 more source

Bidirectional Photoadaptive Organic Heterojunction Synaptic Transistors for Accurate Image Recognition in Machine Vision Systems

Advanced Science, EarlyView.
Bidirectional photoadaptive organic synaptic phototransistors are developed using complementary n–n and n‐p heterojunctions. These devices enable intelligent in‐sensor processing, markedly enhancing image contrast and edge features under adverse lighting, and achieve a recognition accuracy of 97.4% within ten training cycles for machine vision ...
Di Xue, Hongyu Liu, Yingying Zhang, Feng Ding, Jie Lu, Yao Yin, Zi Wang, Jianlong Xu, Lifeng Chi, Lizhen Huang   +9 more
wiley   +1 more source