Results 171 to 180 of about 409,228 (346)
Die gefässlose Stelle der menschlichen Retina und deren Verwerthung zur Bestimmung der Ausdehnung der Macula lutea [PDF]
Demetrius P. Johannides
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The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park+9 more
wiley +1 more source
Case of Pigmented Degeneration of the Retina, Associated with Epileptic Fits [PDF]
F. E. Batten
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Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska+18 more
wiley +1 more source
Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
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Supply Chain Volatility of Repackaged Intravitreal Bevacizumab: A Survey of the American Society of Retina Specialists. [PDF]
Al-Khersan H+12 more
europepmc +1 more source
SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong+9 more
wiley +1 more source
Retraction: RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy. [PDF]
PLOS One Editors.
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