Results 51 to 60 of about 560,151 (337)

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

Hardware Coupled Nonliear Oscillators as a Model of Retina [PDF]

, 1995
An electronic circuit consisting of coupled nonlinear oscillators⁴＇⁵ simulates the spatiotemporal processing in retina. Complex behavior recorded in vivo from ganglion cells in the cat retina 6 in response to flickering light spots is matched by setting ...
Gaudiano, P., Linsay, P.S., Przybyszewski, A.W>, Wilson, C.M.   +3 more
core   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Role of fundus autofluorescence imaging in the management of submacular hemorrhage

BMC Ophthalmology
Purpose To evaluate the baseline characteristics of fundus autofluorescence (FAF) in patients with submacular hemorrhage (SMH). Methods This retrospective study included patients diagnosed with treatment-naive, foveal-involving subretinal hemorrhage ...
Ramesh Venkatesh, Aishwarya Joshi, Sai Prashanthi Chitturi, Ayushi Choudhary, Vishma Prabhu, Snehal Bavaskar, Isha Acharya, Rubble Mangla, Rupal Kathare, Naresh Kumar Yadav, Jay Chhablani   +10 more
doaj   +1 more source

Distribution of melanopsin positive neurons in pigmented and albino mice: evidence for melanopsin interneurons in the mouse retina. [PDF]

, 2014
Here we have studied the population of intrinsically photosensitive retinal ganglion cells (ipRGCs) in adult pigmented and albino mice. Our data show that although pigmented (C57Bl/6) and albino (Swiss) mice have a similar total number of ipRGCs, their ...
Agudo-Barriuso, M, Galindo-Romero, C, García-Ayuso, D, Jiménez-López, M, Ortín-Martínez, A, Valiente-Soriano, FJ, Vidal-Sanz, M, Villegas-Pérez, MP, Vugler, AA   +8 more
core  

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

Advanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño, Carlos Bendicho‐Lavilla, Haya Alfassam, Bárbara Blanco‐Fernández, Abdul W. Basit, Francisco J. Otero‐Espinar   +5 more
wiley   +1 more source

Supervised machine learning statistical models for visual outcome prediction in macular hole surgery: a single-surgeon, standardized surgery study

International Journal of Retina and Vitreous
Purpose To evaluate the predictive accuracy of various machine learning (ML) statistical models in forecasting postoperative visual acuity (VA) outcomes following macular hole (MH) surgery using preoperative optical coherence tomography (OCT) parameters.
Kanika Godani, Vishma Prabhu, Priyanka Gandhi, Ayushi Choudhary, Shubham Darade, Rupal Kathare, Prathiba Hande, Ramesh Venkatesh   +7 more
doaj   +1 more source

Macular Hole Progression after Intravitreal Bevacizumab for Hemicentral Retinal Vein Occlusion

Case Reports in Ophthalmological Medicine, 2011
Macular edema secondary to retinal vein occlusion is commonly being treated with off-label intravitreal bevacizumab with good outcomes. A significant reduction in macular edema and improvement in visual acuity is seen following such a treatment with no ...
Manish Nagpal, Vikram Mehta, Kamal Nagpal   +2 more
doaj   +1 more source

Toxic posterior segment syndrome with retinal vasculitis likely caused by intraocular cotton fiber after vitreoretinal surgery – a case report

BMC Ophthalmology, 2023
Background Intraocular inflammation is common after anterior or posterior segment surgery. They typically manifest either as non-infectious inflammation of the anterior or posterior segment, known as toxic anterior or posterior segment syndrome (TPSS ...
Chaitra Jayadev, Aditi Gupta, Santosh Gopikrishna Gadde, Ramesh Venkatesh   +3 more
doaj   +1 more source

Loss-of-function analysis of EphA receptors in retinotectal mapping [PDF]

, 2004
Peer reviewedPublisher ...
DeChiara, Thomas M., Feldheim, David A., Flanagan, John G., Gale, Nicholas W., Nakamoto, Masaru, Osterfield, Miriam, Rohatgi, Rajat, Yancopoulos, George D.   +7 more
core   +1 more source