Results 61 to 70 of about 698,339 (387)

Glaucoma: the retina and beyond

open access: yesActa Neuropathologica, 2016
Over 60 million people worldwide are diagnosed with glaucomatous optic neuropathy, which is estimated to be responsible for 8.4 million cases of irreversible blindness globally.
B. Davis   +4 more
semanticscholar   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach   +11 more
wiley   +1 more source

Performance of Composite Endpoints Defining Progression Independent of Relapse Activity in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The characteristics and utility of composite progression independent of relapse activity (cPIRA; worsening on the Expanded Disability Status Scale [EDSS], or 9‐Hole Peg Test, or Timed 25‐Foot Walk Test) were evaluated as an endpoint in relapsing multiple sclerosis (RMS) trials using the ENSEMBLE (NCT03085810) and pooled OPERA I/II ...
Ludwig Kappos   +11 more
wiley   +1 more source

Role of fundus autofluorescence imaging in the management of submacular hemorrhage

open access: yesBMC Ophthalmology
Purpose To evaluate the baseline characteristics of fundus autofluorescence (FAF) in patients with submacular hemorrhage (SMH). Methods This retrospective study included patients diagnosed with treatment-naive, foveal-involving subretinal hemorrhage ...
Ramesh Venkatesh   +10 more
doaj   +1 more source

Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

open access: yesJournal of Neuroscience, 2016
Microglia, the principal resident immune cell of the CNS, exert significant influence on neurons during development and in pathological situations. However, if and how microglia contribute to normal neuronal function in the mature uninjured CNS is not ...
Xu Wang   +12 more
semanticscholar   +1 more source

Glioma of the Retina [PDF]

open access: yesThe American Journal of the Medical Sciences, 1902
n ...
openaire   +3 more sources

Comparative Effect of Standard Versus Extended Interval Dosing of Rituximab or Ocrelizumab in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aimed to investigate the comparative effectiveness of standard versus personalized extended interval dosing of anti‐CD20 therapy on clinical and sub‐clinical outcomes in multiple sclerosis. Methods Clinical information was collected prospectively on Research Electronic Data Capture.
Nabil K. El Ayoubi   +6 more
wiley   +1 more source

A minimal statistical-mechanical model for multihyperuniform patterns in avian retina

open access: yes, 2020
Birds are known for their extremely acute sense of vision. The very peculiar structural distribution of five different types of cones in the retina underlies this exquisite ability to sample light.
Guisández, Leandro   +3 more
core   +2 more sources

Electrophysiological Organization of the Eye of Aplysia [PDF]

open access: yes, 1969
The eye of Aplysia californica was studied by electrophysiological and histological methods. It has a central spheroidal lens which is surrounded by a retina composed of several thousand receptor cells which are replete with clear vesicles, pigmented ...
Jacklet, Jon W.
core   +1 more source

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