Results 101 to 110 of about 501,931 (318)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Mutation inBmpr1bLeads to Optic Disc Coloboma and Ventral Retinal Gliosis in Mice

, 2020
Xiaohe Yan, Jenny Atorf, David Ramos‐Barbón, Frank Thiele, Susanne Weber, Claudia Dalke, Minxuan Sun, Oliver Puk, Dian Michel, Helmut Fuchs, Matthias Klaften, Gerhard K. H. Przemeck, Sibylle Sabrautzki, Jack Favor, Jesús Ruberte, Jan Kremers, Martin Hrabě de Angelis, Jochen Graw   +17 more
openalex   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Intravitreal Co-Administration of GDNF and CNTF Confers Synergistic and Long-Lasting Protection against Injury-Induced Cell Death of Retinal Ganglion Cells in Mice [PDF]

, 2020
Simon Dulz, Mahmoud Bassal, Kai Flachsbarth, Kristoffer Riecken, Boris Fehse, Stefanie Schlichting, Susanne Bartsch, Udo Bartsch   +7 more
openalex   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

Identification of epiretinal proliferation in various retinal diseases and vitreoretinal interface disorders [PDF]

, 2020
Ismaël Chehaibou, Moritz Pettenkofer, Andrea Govetto, Gilad Rabina, Srinivas R. Sadda, Jean‐Pierre Hubschman   +5 more
openalex   +1 more source

Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring

Advanced Materials Technologies, EarlyView.
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim, Yu‐Jen Cheng, Tianyi Li, Nathan White, Xu Wang, Kristyn Ringgold, Lauren Neidig, Younghoon Kwon, Jae‐Hyun Chung   +8 more
wiley   +1 more source

Submicron Patterning Techniques for Perovskite Optoelectronics From Materials Challenges to Scalable Device Integration

Advanced Optical Materials, EarlyView.
This review highlights submicron patterning strategies for metal halide perovskites, focusing on solvent compatibility, resolution, and alignment toward scalable integration in advanced optoelectronic systems. Abstract Halide perovskites are promising materials for future optoelectronic and display systems.
Dante Ahn, Minz Lee, Youngsoo Jang, Gun Young Jung, Yusin Pak   +4 more
wiley   +1 more source

Ultra‐Flexible Dual‐Band Organic Photodetectors for Visible and Near‐Infrared Sensing

Advanced Optical Materials, EarlyView.
An ultra‐flexible dual‐band organic photodetector with a total thickness of 5.6 µm for bio‐sensing is developed. It selectively detects visible and near‐infrared light with high sensitivity by switching the voltage. Peripheral oxygen saturation (SpO2) measurement is demonstrated using the device attached to a finger under a single light source by ...
Sachi Awakura, Hiroaki Jinno, Yusaku Tagawa, Ryota Fukuzawa, Masahito Takakuwa, Takao Someya, Tomoyuki Yokota   +6 more
wiley   +1 more source

Flexible Sensor‐Based Human–Machine Interfaces with AI Integration for Medical Robotics

Advanced Robotics Research, EarlyView.
This review explores how flexible sensing technology and artificial intelligence (AI) significantly enhance human–machine interfaces in medical robotics. It highlights key sensing mechanisms, AI‐driven advancements, and applications in prosthetics, exoskeletons, and surgical robotics.
Yuxiao Wang, Zhipeng Jiang, Sun Hwa Kwon, Matthew Ibrahim, Alexander Dang, Lin Dong   +5 more
wiley   +1 more source